A promoter types
Schichman et al., 1993 organized a
variety of A promoter monomer sequences into an
evolutionary series.
They presented a consensus of each type as below. I have annotated the
description with where they fall on the 3' sequence tree.
- Type I: Found on the terminal burst of A2. An array
of type I is usually connected to the body through a type III monomer.
- Type II: Found on slightly older members of the A2
lineage but after the A2:TF/L1Md4 split. An array of type II monomers is usually connected to the body through a type IV monomer.
- Type III: The m1 copy on the terminal burst of the A2 lineage.
- Type IV: Found as the m1 element of the A2 lineage between the A2:TF/L1Md4 split together with type II monomers. Found as a IV-IV dimer at the very top of the A2 lineage below the A2:TF/L1Md4 split.
- Type V: Probably the ancestral type. Not localized with respect to the 3' sequence tree.
- Type VI: Found in an AF composite clade as an array of type VI A monomers connected to an F-type m1. This group is tentatively assigned to the L1Md2 lineage.
- Type VIm1: Get from AF composite sequences of A12, pg14LH, and AF37352b; same as Type VI except 14 bases have been removed from the end. See Alignment
See Alignment taken from Schichman et al.