Telephone: 210-562-6135 E-mail: ChaudhuriA@uthscsa.edu
Molecular mechanism of protein oxidation and structural alteration in aging and age-related diseases
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Asish Chaudhuri, Assistant
Professor/Research;
Telephone: 210-562-6135 E-mail: ChaudhuriA@uthscsa.edu Molecular mechanism of protein oxidation and structural alteration in aging and age-related diseases |
Viviana Perez, Christie M Lew, Lisa A Cortez, Celeste R Webb, Marisela Rodriguez, Yuhong Liu, Wenbo Qi, Yan Li, Asish Chaudhuri, Holly Van Remmen, Arlan Richardson and Yuji Ikeno (2007) Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress. Free Radical Biol. Med. In press.
Pierce
AP, de Waal E, McManus LM, Shireman PK, Chaudhuri AR.
Oxidation and structural perturbation of redox-sensitive enzymes in
injured skeletal muscle.
Free Radic Biol Med. 2007 Dec 15;43(12):1584-1593. Epub 2007
Sep 4.
PMID: 18037124
Zhang
Y, Padalecki SS, Chaudhuri AR, De Waal E, Goins BA, Grubbs B, Ikeno Y,
Richardson A, Mundy GR, Herman B.
Caspase-2 deficiency enhances aging-related traits in mice.
Mech Ageing Dev. 2007 Feb;128(2):213-21. Epub 2006 Dec 22.
PMID: 17188333
Andziak
B, O'Connor TP, Qi W, DeWaal EM, Pierce A, Chaudhuri AR, Van Remmen H,
Buffenstein R.
High oxidative damage levels in the longest-living rodent, the naked
mole-rat.
Aging Cell. 2006 Dec;5(6):463-71. Epub 2006 Oct 27.
PMID: 17054663
Chaudhuri
AR, de Waal EM, Pierce A, Van Remmen H, Ward WF, Richardson A.
Detection of protein carbonyls in aging liver tissue: A fluorescence-based
proteomic approach.
Mech Ageing Dev. 2006 Nov;127(11):849-61. Epub 2006 Sep 26.
PMID: 17002888
Muller
FL, Song W, Liu Y, Chaudhuri A, Pieke-Dahl S, Strong R, Huang TT, Epstein
CJ, Roberts LJ 2nd, Csete M, Faulkner JA, Van Remmen H.
Absence of CuZn superoxide dismutase leads to elevated oxidative stress
and acceleration of age-dependent skeletal muscle atrophy.
Free Radic Biol Med. 2006 Jun 1;40(11):1993-2004. Epub 2006
Feb 17.
PMID: 16716900
Pierce
A, deWaal E, Van Remmen H, Richardson A, Chaudhuri A.
A novel approach for screening the proteome for changes in protein
conformation.
Biochemistry. 2006 Mar 7;45(9):3077-85. Erratum in: Biochemistry.
2006 May 2;45(17):5686. VanRemmen, Holly [corrected to Van Remmen, Holly].
PMID: 16503663
Bokov
A, Chaudhuri A, Richardson A.
The role of oxidative damage and stress in aging.
Mech Ageing Dev. 2004 Oct-Nov;125(10-11):811-26. Review.
PMID: 15541775
Chaudhuri
AR, Khan IA, Luduena RF.
Detection of disulfide bonds in bovine brain tubulin and their role
in protein folding and microtubule assembly in vitro: a novel disulfide
detection approach.
Biochemistry. 2001 Jul 31;40(30):8834-41.
PMID: 11467944
Chaudhuri
AR, Seetharamalu P, Schwarz PM, Hausheer FH, Luduena RF.
The interaction of the B-ring of colchicine with alpha-tubulin: a novel
footprinting approach.
J Mol Biol. 2000 Nov 10;303(5):679-92.
PMID: 11061968
Prasad
V, Scotch R, Chaudhuri AR, Walss C, Fathy DB, Miller C, Luduena RF.
Interactions of bovine brain tubulin with pyridostigmine bromide and
N,N'-diethyl-m-toluamide.
Neurochem Res. 2000 Jan;25(1):19-25.
PMID: 10685600
Chaudhuri
AR, Khan IA, Prasad V, Robinson AK, Luduena RF, Barnes LD.
The tumor suppressor protein Fhit. A novel interaction with tubulin.
J Biol Chem. 1999 Aug 20;274(34):24378-82.
PMID: 10446217
Chaudhuri
AR, Tomita I, Mizuhashi F, Murata K, Potenziano JL, Luduena RF.
IKP104-induced decay of tubulin: role of the A-ring binding site of
colchicine.
Biochemistry. 1998 Dec 8;37(49):17157-62.
PMID: 9860828
Chaudhuri
AR, Tomita I, Mizuhashi F, Murata K, Luduena RF.
Distinct and overlapping binding sites for IKP104 and vinblastine on
tubulin.
J Protein Chem. 1998 Oct;17(7):685-90.
PMID: 9853684
Prasad
V, Chaudhuri AR, Curcio M, Tomita I, Mizuhashi F, Murata K, Luduena RF.
Podophyllotoxin and nocodazole counter the effect of IKP104 on tubulin
decay.
J Protein Chem. 1998 Oct;17(7):663-8.
PMID: 9853681
Chaudhuri
AR, Tomita I, Mizuhashi F, Murata K, Luduena RF.
Tubulin stability and decay: mediation by two distinct classes of IKP104-binding
sites.
J Protein Chem. 1998 May;17(4):303-9.
PMID: 9619583
Chaudhuri
AR, Luduena RF.
Interaction of phomopsin A with normal and subtilisin-treated bovine
brain tubulin.
J Protein Chem. 1997 Feb;16(2):99-105.
PMID: 9112603
Chaudhuri
AR, Luduena RF.
Griseofulvin: a novel interaction with bovine brain tubulin.
Biochem Pharmacol. 1996 Apr 12;51(7):903-9.
PMID: 8651940
Luduena
RF, Roach MC, Prasad V, Chaudhuri AR, Tomita I, Mizuhashi F, Murata K.
Interaction of bovine brain tubulin with the 4(1H)-pyrizinone derivative
IKP104, an antimitotic drug with a complex set of effects on the conformational
stability of the tubulin molecule.
Biochemistry. 1995 Dec 5;34(48):15751-9.
PMID: 7495806
Chaudhuri
AR, Biswas S.
Cold stability of microtubules of Mimosa pudica.
Biochem Mol Biol Int. 1993 Mar;29(3):421-8.
PMID: 8485459
Roychaudhuri
A, Biswas S.
Sulfhydryl groups of Mimosa pudica tubulin implicated in colchicine
binding and polymerization in vitro.
Arch Biochem Biophys. 1992 May 1;294(2):353-60.
PMID: 1567190
Pal
M, Roychaudhury A, Pal A, Biswas S.
A novel tubulin from Mimosa pudica. Purification and characterization.
Eur J Biochem. 1990 Sep 11;192(2):329-35.
PMID: 2209590