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Franco Folli, Associate
Professor; M.D., Ph.D.
Telephone: (210) 567-4826 E-mail: folli@uthscsa.edu The baboon represents a non-human primate which develops diabetes mellitus and obesity very similarly to humans. We have characterized physiologic and molecular mechanisms of insulin action and insulin secretion in this species. Baboons are 98 % genetically similar to humans and therefore represent the ideal model to study metabolic diseases and new treatments that could eventually be employed in humans. My laboratory is also interested in studying novel mechanisms of insulin resistance and defective insulin secretion in humans affected by obesity and type 2 diabetes, employing an in-vivo physiology approaches coupled with subcellular proteomics and genomics. |
Perani
D, Garibotto V, Moresco RM, Ortelli P, Corbo M, Fazio F, Folli F.
PET evidence of central GABAergic changes in stiff-person syndrome.
Mov Disord. 2007 May 15;22(7):1030-3.
PMID: 17575583
Folli
F, Pontiroli AE, Schwesinger WH.
Metabolic aspects of bariatric surgery.
Med Clin North Am. 2007 May;91(3):393-414, x. Review.
PMID: 17509385
Prudente
S, Flex E, Morini E, Turchi F, Capponi D, De Cosmo S, Tassi V, Guida V,
Avogaro A, Folli F, Maiani F, Frittitta L, Dallapiccola B, Trischitta V.
A functional variant of the adipocyte glycerol channel aquaporin 7
gene is associated with obesity and related metabolic abnormalities.
Diabetes. 2007 May;56(5):1468-74. Epub 2007 Mar 9.
PMID: 17351148
Pontiroli
AE, Pizzocri P, Paroni R, Folli F.
Sympathetic overactivity, endothelial dysfunction, inflammation, and
metabolic abnormalities cluster in grade III (World Health Organization)
obesity: reversal through sustained weight loss obtained with laparoscopic
adjustable gastric banding.
Diabetes Care. 2006 Dec;29(12):2735-8. No abstract available.
PMID: 17130217
Folli
F, Galimberti G, Pastore M, Davalli AM, Bosi E.
Paraneoplastic insulin resistance syndrome in advanced aggressive fibromatosis
(desmoid tumor) treated by imatinib mesylate.
Diabetes Care. 2006 Sep;29(9):2178-80. No abstract available.
PMID: 16936177
Velloso
LA, Folli F, Perego L, Saad MJ.
The multi-faceted cross-talk between the insulin and angiotensin II
signaling systems.
Diabetes Metab Res Rev. 2006 Mar-Apr;22(2):98-107. Review.
PMID: 16389635
Scavini
M, Pontiroli AE, Folli F.
Asymptomatic hyperinsulinemic hypoglycemia after gastric banding.
N Engl J Med. 2005 Dec 29;353(26):2822-3. No abstract available.
PMID: 16382076
Finzi
G, Davalli A, Placidi C, Usellini L, La Rosa S, Folli F, Capella C.
Morphological and ultrastructural features of human islet grafts performed
in
diabetic nude mice.
Ultrastruct Pathol. 2005 Nov-Dec;29(6):525-33.
PMID: 16316953
Pontiroli
AE, Folli F, Paganelli M, Micheletto G, Pizzocri P, Vedani P, Luisi F,
Perego L, Morabito A, Bressani Doldi S.
Laparoscopic gastric banding prevents type 2 diabetes and arterial
hypertension and induces their remission in morbid obesity: a 4-year case-controlled
study.
Diabetes Care. 2005 Nov;28(11):2703-9.
PMID: 16249543
Fiorina
P, Folli F, Ferrero E, Orsenigo E, Finzi G, Mazzolari G, Placidi C, Perego
L, La Rosa S, Melandri M, Monti L, Capella C, D'Angelo A, Staudacher C,
Secchi A.
Morphological and functional differences in haemostatic axis between
kidney transplanted and end-stage renal disease patients.
Transpl Int. 2005 Sep;18(9):1036-47.
PMID: 16101724
Cardellini
M, Perego L, D'Adamo M, Marini MA, Procopio C, Hribal ML, Andreozzi F,
Frontoni S, Giacomelli M, Paganelli M, Pontiroli AE, Lauro R, Folli F,
Sesti G.
C-174G polymorphism in the promoter of the interleukin-6 gene is associated
with insulin resistance.
Diabetes Care. 2005 Aug;28(8):2007-12.
PMID: 16043746
Sesti
G, Perego L, Cardellini M, Andreozzi F, Ricasoli C, Vedani P, Guzzi V,
Marchi M, Paganelli M, Ferla G, Pontiroli AE, Hribal ML, Folli F.
Impact of common polymorphisms in candidate genes for insulin resistance
and obesity on weight loss of morbidly obese subjects after laparoscopic
adjustable gastric banding and hypocaloric diet.
J Clin Endocrinol Metab. 2005 Sep;90(9):5064-9. Epub 2005 Jun
28. Erratum in: J Clin Endocrinol Metab. 2005 Oct;90(10):5810.
PMID: 15985484
Fiorina
P, Gremizzi C, Maffi P, Caldara R, Tavano D, Monti L, Socci C, Folli F,
Fazio F, Astorri E, Del Maschio A, Secchi A.
Islet transplantation is associated with an improvement of cardiovascular
function in type 1 diabetic kidney transplant patients.
Diabetes Care. 2005 Jun;28(6):1358-65.
PMID: 15920052
Fiorina
P, Venturini M, Folli F, Losio C, Maffi P, Placidi C, La Rosa S, Orsenigo
E, Socci C, Capella C, Del Maschio A, Secchi A.
Natural history of kidney graft survival, hypertrophy, and vascular
function in end-stage renal disease type 1 diabetic kidney-transplanted
patients: beneficial impact of pancreas and successful islet cotransplantation.
Diabetes Care. 2005 Jun;28(6):1303-10.
PMID: 15920043
Perego
L, Pizzocri P, Corradi D, Maisano F, Paganelli M, Fiorina P, Barbieri M,
Morabito A, Paolisso G, Folli F, Pontiroli AE.
Circulating leptin correlates with left ventricular mass in morbid
(grade III) obesity before and after weight loss induced by bariatric surgery:
a potential role for leptin in mediating human left ventricular hypertrophy.
J Clin Endocrinol Metab. 2005 Jul;90(7):4087-93. Epub 2005 Apr
26.
PMID: 15855267
Ueno
M, Carvalheira JB, Tambascia RC, Bezerra RM, Amaral ME, Carneiro EM, Folli
F, Franchini KG, Saad MJ.
Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2
serine phosphorylation and the mTOR/p70 S6K pathway.
Diabetologia. 2005 Mar;48(3):506-18. Epub 2005 Feb 4.
PMID: 15692808
Veronelli
A, Laneri M, Ranieri R, Koprivec D, Vardaro D, Paganelli M, Folli F, Pontiroli
AE.
White blood cells in obesity and diabetes: effects of weight loss and
normalization of glucose metabolism.
Diabetes Care. 2004 Oct;27(10):2501-2. No abstract available.
PMID: 15451926
Fiorina
P, Folli F, D'Angelo A, Finzi G, Pellegatta F, Guzzi V, Fedeli C, Della
Valle P, Usellini L, Placidi C, Bifari F, Belloni D, Ferrero E, Capella
C, Secchi A.
Normalization of multiple hemostatic abnormalities in uremic type 1
diabetic patients after kidney-pancreas transplantation.
Diabetes. 2004 Sep;53(9):2291-300.
PMID: 15331538
Fiorina
P, Corradi D, Pinelli S, Maestri R, Lagrasta C, Buscaglia M, Davalli A,
Folli F, Astorri E.
Apoptotic/mytogenic pathways during human heart development.
Int J Cardiol. 2004 Sep;96(3):409-17.
PMID: 15301895
D'Adamo
M, Perego L, Cardellini M, Marini MA, Frontoni S, Andreozzi F, Sciacqua
A, Lauro D, Sbraccia P, Federici M, Paganelli M, Pontiroli AE, Lauro R,
Perticone F, Folli F, Sesti G.
The -866A/A genotype in the promoter of the human uncoupling protein
2 gene is associated with insulin resistance and increased risk of type
2 diabetes.
Diabetes. 2004 Jul;53(7):1905-10.
PMID: 15220218
Svegliati-Baroni
G, Ridolfi F, Caradonna Z, Alvaro D, Marzioni M, Saccomanno S, Candelaresi
C, Trozzi L, Macarri G, Benedetti A, Folli F.
Regulation of ERK/JNK/p70S6K in two rat models of liver injury and
fibrosis.
J Hepatol. 2003 Oct;39(4):528-37.
PMID: 12971962
Fiorina
P, Folli F, Zerbini G, Maffi P, Gremizzi C, Di Carlo V, Socci C, Bertuzzi
F, Kashgarian M, Secchi A.
Islet transplantation is associated with improvement of renal function
among uremic patients with type I diabetes mellitus and kidney transplants.
J Am Soc Nephrol. 2003 Aug;14(8):2150-8.
PMID: 12874470
Hribal
ML, Perego L, Lovari S, Andreozzi F, Menghini R, Perego C, Finzi G, Usellini
L, Placidi C, Capella C, Guzzi V, Lauro D, Bertuzzi F, Davalli A, Pozza
G, Pontiroli A, Federici M, Lauro R, Brunetti A, Folli F, Sesti G.
Chronic hyperglycemia impairs insulin secretion by affecting insulin
receptor expression, splicing, and signaling in RIN beta cell line and
human islets of Langerhans.
FASEB J. 2003 Jul;17(10):1340-2. Epub 2003 May 8.
PMID: 12738810
Fiorina
P, Folli F, Maffi P, Placidi C, Venturini M, Finzi G, Bertuzzi F, Davalli
A, D'Angelo A, Socci C, Gremizzi C, Orsenigo E, La Rosa S, Ponzoni M, Cardillo
M, Scalamogna M, Del Maschio A, Capella C, Di Carlo V, Secchi A.
Islet transplantation improves vascular diabetic complications in patients
with diabetes who underwent kidney transplantation: a comparison between
kidney-pancreas and kidney-alone transplantation.
Transplantation. 2003 Apr 27;75(8):1296-301.
PMID: 12717219
Carvalheira
JB, Ribeiro EB, Folli F, Velloso LA, Saad MJ.
Interaction between leptin and insulin signaling pathways differentially
affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver.
Biol Chem. 2003 Jan;384(1):151-9.
PMID: 12674509
Fiorina
P, Folli F, Bertuzzi F, Maffi P, Finzi G, Venturini M, Socci C, Davalli
A, Orsenigo E, Monti L, Falqui L, Uccella S, La Rosa S, Usellini L, Properzi
G, Di Carlo V, Del Maschio A, Capella C, Secchi A.
Long-term beneficial effect of islet transplantation on diabetic macro-/microangiopathy
in type 1 diabetic kidney-transplanted patients.
Diabetes Care. 2003 Apr;26(4):1129-36.
PMID: 12663585
Polastri
L, Galbiati F, Folli F, Davalli AM.
Effects of carboxypeptidase E overexpression on insulin mRNA levels,
regulated insulin secretion, and proinsulin processing of pituitary GH3
cells transfected with a furin-cleavable human proinsulin cDNA.
Cell Transplant. 2002;11(8):803-11.
PMID: 12588113
Pontiroli
AE, Pizzocri P, Giacomelli M, Marchi M, Vedani P, Cucchi E, Orena C, Folli
F, Paganelli M, Ferla G.
Ultrasound measurement of visceral and subcutaneous fat in morbidly
obese patients before and after laparoscopic adjustable gastric banding:
comparison with computerized tomography and with anthropometric measurements.
Obes Surg. 2002 Oct;12(5):648-51.
PMID: 12448386
Folli
F, Perego L, Ponzoni M, Girardi AM, Bosi E, Ferreri AJ, Bellone M, Sabbadini
MG, Vicari AM, Trusolino L.
Autoantibodies against a 72-kDa ductal cell membrane glycoprotein in
a patient affected by Sjogren's syndrome and gastric MALT lymphoma.
Ann Hematol. 2002 Oct;81(10):597-602. Epub 2002 Sep 24. Erratum
in: Ann Hematol. 2003 Mar;82(3):203.
PMID: 12424543
Galbiati
F, Polastri L, Gregori S, Freschi M, Casorati M, Cavallaro U, Fiorina P,
Bertuzzi F, Zerbi A, Pozza G, Adorini L, Folli F, Christofori G, Davalli
AM.
Antitumorigenic and antiinsulinogenic effects of calcitriol on insulinoma
cells and solid beta-cell tumors.
Endocrinology. 2002 Oct;143(10):4018-30.
PMID: 12239113
Pontiroli
AE, Pizzocri P, Folli F.
Plasma leptin levels and coronary heart disease.
Circulation. 2002 Aug 27;106(9):e42; author reply e42. No abstract
available.
PMID: 12196352
Pontiroli
AE, Pizzocri P, Librenti MC, Vedani P, Marchi M, Cucchi E, Orena C, Paganelli
M, Giacomelli M, Ferla G, Folli F.
Laparoscopic adjustable gastric banding for the treatment of morbid
(grade 3) obesity and its metabolic complications: a three-year study.
J Clin Endocrinol Metab. 2002 Aug;87(8):3555-61.
PMID: 12161474
Alvaro
D, Alpini G, Onori P, Franchitto A, Glaser SS, Le Sage G, Folli F, Attili
AF, Gaudio E.
Alfa and beta estrogen receptors and the biliary tree.
Mol Cell Endocrinol. 2002 Jul 31;193(1-2):105-8. Review.
PMID: 12161009
Alvaro
D, Onori P, Metalli VD, Svegliati-Baroni G, Folli F, Franchitto A, Alpini
G, Mancino MG, Attili AF, Gaudio E.
Intracellular pathways mediating estrogen-induced cholangiocyte proliferation
in the rat.
Hepatology. 2002 Aug;36(2):297-304.
PMID: 12143037
Perego
L, Previtali SC, Nemni R, Longhi R, Carandente O, Saibene A, Sciolla R,
Villa A, Gai P, Panzeri C, Dell'Antonio G, Quattrini A, Folli F.
Autoantibodies to amphiphysin I and amphiphysin II in a patient with
sensory-motor neuropathy.
Eur Neurol. 2002;47(4):196-200.
PMID: 12037431
Ponzoni
M, Patriarca C, Arrigoni G, Gianelli U, Vicari A, Folli F.
Extramedullary myeloid cell tumor/granulocytic sarcoma with predilection
for serosal surfaces.
Haematologica. 2002 Mar;87(3):ECR09. No abstract available.
PMID: 11869955
Chiellini
C, Bertacca A, Novelli SE, Gorgun CZ, Ciccarone A, Giordano A, Xu H, Soukas
A, Costa M, Gandini D, Dimitri R, Bottone P, Cecchetti P, Pardini E, Perego
L, Navalesi R, Folli F, Benzi L, Cinti S, Friedman JM, Hotamisligil GS,
Maffei M.
Obesity modulates the expression of haptoglobin in the white adipose
tissue via TNFalpha.
J Cell Physiol. 2002 Feb;190(2):251-8.
PMID: 11807829
Pizzocri
P, Koprivec D, Folli F, Vedani P, Marchi M, Paganelli M, Pontiroli AE.
Changes in lipid levels with percent of weight loss in morbid obesity.
Obes Surg. 2001 Oct;11(5):649-50. No abstract available.
PMID: 11594114
Pellegatta
F, Radaelli A, Heltai S, Yan L, Chierchia SL, Folli F.
Evidence for the involvement of phosphatidylinositol 3-kinase in fMLP-stimulated
neutrophil adhesion to ICAM-1-transfected cells.
J Cardiovasc Pharmacol. 2001 Jun;37(6):751-61.
PMID: 11392472
Federici
M, Hribal M, Perego L, Ranalli M, Caradonna Z, Perego C, Usellini L, Nano
R, Bonini P, Bertuzzi F, Marlier LN, Davalli AM, Carandente O, Pontiroli
AE, Melino G, Marchetti P, Lauro R, Sesti G, Folli F.
High glucose causes apoptosis in cultured human pancreatic islets of
Langerhans: a potential role for regulation of specific Bcl family genes
toward an apoptotic cell death program.
Diabetes. 2001 Jun;50(6):1290-301.
PMID: 11375329
Davalli
AM, Galbiati F, Bertuzzi F, Polastri L, Pontiroli AE, Perego L, Freschi
M, Pozza G, Folli F, Meoni C.
Insulin-secreting pituitary GH3 cells: a potential beta-cell surrogate
for diabetes cell therapy.
Cell Transplant. 2000 Nov-Dec;9(6):841-51.
PMID: 11202570
Meoni
C, Bertuzzi F, Pontiroli AE, Falqui L, Monaco L, Soria M, Arcelloni C,
Paroni
R, Foglieni C, Polastri L, Galbiati F, Folli F, Davalli AM.
Development and characterization of pituitary GH3 cell clones stably
transfected with a human proinsulin cDNA.
Cell Transplant. 2000 Nov-Dec;9(6):829-40.
PMID: 11202569
Alvaro
D, Alpini G, Onori P, Perego L, Svegliata Baroni G, Franchitto A, Baiocchi
L, Glaser SS, Le Sage G, Folli F, Gaudio E.
Estrogens stimulate proliferation of intrahepatic biliary epithelium
in rats.
Gastroenterology. 2000 Dec;119(6):1681-91.
PMID: 11113090
Svegliati-Baroni
G, Ridolfi F, Di Sario A, Casini A, Marucci L, Gaggiotti G, Orlandoni P,
Macarri G, Perego L, Benedetti A, Folli F.
Insulin and insulin-like growth factor-1 stimulate proliferation and
type I collagen accumulation by human hepatic stellate cells: differential
effects on signal transduction pathways.
Hepatology. 1999 Jun;29(6):1743-51.
PMID: 10347117
Folli
F, Saad MJ, Velloso L, Hansen H, Carandente O, Feener EP, Kahn CR.
Crosstalk between insulin and angiotensin II signalling systems.
Exp Clin Endocrinol Diabetes. 1999;107(2):133-9. Review.
PMID: 10320054
Pigazzi
A, Heydrick S, Folli F, Benoit S, Michelson A, Loscalzo J.
Nitric oxide inhibits thrombin receptor-activating peptide-induced
phosphoinositide 3-kinase activity in human platelets.
J Biol Chem. 1999 May 14;274(20):14368-75.
PMID: 10318860
Pontiroli
AE, Folli F.
Is it worth treating diabetes? Lessons from the UKPDS. United Kingdom
Prospective Diabetes Study.
Acta Diabetol. 1998 Dec;35(4):170-1. No abstract available.
PMID: 9934813
Velloso
LA, Carvalho CR, Rojas FA, Folli F, Saad MJ.
Insulin signalling in heart involves insulin receptor substrates-1
and -2, activation of phosphatidylinositol 3-kinase and the JAK 2-growth
related pathway.
Cardiovasc Res. 1998 Oct;40(1):96-102.
PMID: 9876321
Folli
F.
Stiff man syndrome, 40 years later.
J Neurol Neurosurg Psychiatry. 1998 Nov;65(5):618. No abstract
available.
PMID: 9810927
Manfredi
PL, Herskovitz S, Folli F, Pigazzi A, Swerdlow ML.
Spinal epidural abscess: treatment options.
Eur Neurol. 1998 Jul;40(1):58-60. No abstract available.
PMID: 9729116
Vicari
AM, Ponzoni M, Alberetto M, Martani C, Pontiroli AE, Folli F.
Erythrocytosis in a patient with chronic obstructive pulmonary disease.
Haematologica. 1998 Feb;83(2):183-6.
PMID: 9549929
Vicari
AM, Ciceri F, Folli F, Lanzi R, Colombo B, Comi G, Camba L.
Acute promyelocytic leukemia following mitoxantrone as single agent
for the treatment of multiple sclerosis.
Leukemia. 1998 Mar;12(3):441-2. No abstract available.
PMID: 9529141
Gerra
G, Zaimovic A, Giucastro G, Folli F, Maestri D, Tessoni A, Avanzini P,
Caccavari R, Bernasconi S, Brambilla F.
Neurotransmitter-hormonal responses to psychological stress in peripubertal
subjects: relationship to aggressive behavior.
Life Sci. 1998;62(7):617-25.
PMID: 9472721
Folli
F, Kahn CR, Hansen H, Bouchie JL, Feener EP.
Angiotensin II inhibits insulin signaling in aortic smooth muscle cells
at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin
II crosstalk.
J Clin Invest. 1997 Nov 1;100(9):2158-69.
PMID: 9410892
Folli
F, Alvaro D, Gigliozzi A, Bassotti C, Kahn CR, Pontiroli AE, Capocaccia
L, Jezequel AM, Benedetti A.
Regulation of endocytic-transcytotic pathways and bile secretion by
phosphatidylinositol 3-kinase in rats.
Gastroenterology. 1997 Sep;113(3):954-65.
PMID: 9287989
Folli
F, Ponzoni M, Vicari AM.
Paraneoplastic autoimmune xerostomia.
Ann Intern Med. 1997 Jul 15;127(2):167-8. No abstract available.
PMID: 9230018
Velloso
LA, Folli F, Sun XJ, White MF, Saad MJ, Kahn CR.
Cross-talk between the insulin and angiotensin signaling systems.
Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12490-5.
PMID: 8901609
Folli
F, Ghidella S, Bonfanti L, Kahn CR, Merighi A.
The early intracellular signaling pathway for the insulin/insulin-like
growth factor receptor family in the mammalian central nervous system.
Mol Neurobiol. 1996 Oct;13(2):155-83. Review.
PMID: 8938649
Vicari
AM, Taglietti MV, Pellegatta F, Spotti D, Melandri M, Galli L, Ronchi P,
Folli F.
Deranged platelet calcium homeostasis in diabetic patients with end-stage
renal failure. A possible link to increased cardiovascular mortality?
Diabetes Care. 1996 Oct;19(10):1062-6.
PMID: 8886550
Folli
F, Saad MJ, Kahn CR.
Insulin receptor/IRS-1/PI 3-kinase signaling system in corticosteroid-induced
insulin resistance.
Acta Diabetol. 1996 Sep;33(3):185-92. Review. No abstract available.
PMID: 8904923
Goldfine
AB, Simonson DC, Folli F, Patti ME, Kahn CR.
In vivo and in vitro studies of vanadate in human and rodent diabetes
mellitus.
Mol Cell Biochem. 1995 Dec 6-20;153(1-2):217-31. Review.
PMID: 8927042
Goldfine
AB, Simonson DC, Folli F, Patti ME, Kahn CR.
Metabolic effects of sodium metavanadate in humans with insulin-dependent
and noninsulin-dependent diabetes mellitus in vivo and in vitro studies.
J Clin Endocrinol Metab. 1995 Nov;80(11):3311-20.
PMID: 7593444
Saad
MJ, Folli F, Kahn CR.
Insulin and dexamethasone regulate insulin receptors, insulin receptor
substrate-1, and phosphatidylinositol 3-kinase in Fao hepatoma cells.
Endocrinology. 1995 Apr;136(4):1579-88.
PMID: 7895667
Folli
F, Bonfanti L, Renard E, Kahn CR, Merighi A.
Insulin receptor substrate-1 (IRS-1) distribution in the rat central
nervous system.
J Neurosci. 1994 Nov;14(11 Pt 1):6412-22.
PMID: 7965046
Vicari
AM, Monzani ML, Pellegatta F, Ronchi P, Galli L, Folli F.
Platelet calcium homeostasis is abnormal in patients with severe arteriosclerosis.
Arterioscler Thromb. 1994 Sep;14(9):1420-4.
PMID: 8068602
Saad
MJ, Folli F, Araki E, Hashimoto N, Csermely P, Kahn CR.
Regulation of insulin receptor, insulin receptor substrate-1 and phosphatidylinositol
3-kinase in 3T3-F442A adipocytes. Effects of differentiation, insulin,
and dexamethasone.
Mol Endocrinol. 1994 May;8(5):545-57.
PMID: 7520127
De
Camilli P, Thomas A, Cofiell R, Folli F, Lichte B, Piccolo G, Meinck HM,
Austoni M, Fassetta G, Bottazzo G, et al.
The synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen
of Stiff-Man syndrome with breast cancer.
J Exp Med. 1993 Dec 1;178(6):2219-23.
PMID: 8245793
Saad
MJ, Folli F, Kahn JA, Kahn CR.
Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol
3-kinase in liver and muscle of dexamethasone-treated rats.
J Clin Invest. 1993 Oct;92(4):2065-72.
PMID: 7691892
Folli
F, Saad MJ, Backer JM, Kahn CR.
Regulation of phosphatidylinositol 3-kinase activity in liver and muscle
of animal models of insulin-resistant and insulin-deficient diabetes mellitus.
J Clin Invest. 1993 Oct;92(4):1787-94.
PMID: 7691886
Folli
F, Solimena M, Cofiell R, Austoni M, Tallini G, Fassetta G, Bates D, Cartlidge
N, Bottazzo GF, Piccolo G, et al.
Autoantibodies to a 128-kd synaptic protein in three women with the
stiff-man syndrome and breast cancer.
N Engl J Med. 1993 Feb 25;328(8):546-51.
PMID: 8381208
Pellegatta
F, Folli F, Ronchi P, Caspani L, Galli L, Vicari AM.
Deranged platelet calcium homeostasis in poorly controlled IDDM patients.
Diabetes Care. 1993 Jan;16(1):178-83.
PMID: 8422772
Kahn
CR, White MF, Shoelson SE, Backer JM, Araki E, Cheatham B, Csermely P,
Folli F, Goldstein BJ, Huertas P, et al.
The insulin receptor and its substrate: molecular determinants of early
events in insulin action.
Recent Prog Horm Res. 1993;48:291-339. Review. No abstract available.
PMID: 7680139
Kahn
CR, Folli F.
Molecular determinants of insulin action.
Horm Res. 1993;39 Suppl 3:93-101. Review.
PMID: 7505252
Folli
F, Saad MJ, Backer JM, Kahn CR.
Insulin stimulation of phosphatidylinositol 3-kinase activity and association
with insulin receptor substrate 1 in liver and muscle of the intact rat.
J Biol Chem. 1992 Nov 5;267(31):22171-7.
PMID: 1385396
Reetz
A, Solimena M, Matteoli M, Folli F, Takei K, De Camilli P.
GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase
(GAD) and GABA with synaptic-like microvesicles suggests their role in
GABA storage and secretion.
EMBO J. 1991 May;10(5):1275-84.
PMID: 2022191
Baekkeskov
S, Aanstoot HJ, Christgau S, Reetz A, Solimena M, Cascalho M, Folli F,
Richter-Olesen H, De Camilli P.
Identification of the 64K autoantigen in insulin-dependent diabetes
as the GABA-synthesizing enzyme glutamic acid decarboxylase.
Nature. 1990 Sep 13;347(6289):151-6. Erratum in: Nature 1990
Oct 25;347(6295):782. Camilli, PD [corrected to De Camilli, P].
PMID: 1697648
Solimena
M, Folli F, Aparisi R, Pozza G, De Camilli P.
Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man
syndrome.
N Engl J Med. 1990 May 31;322(22):1555-60.
PMID: 2135382