Franco Folli, Associate Professor; M.D., Ph.D.
Telephone: (210) 567-4826 E-mail: folli@uthscsa.edu

The baboon represents a non-human primate which develops diabetes mellitus and obesity very similarly to humans. We have characterized physiologic and molecular mechanisms of insulin action and insulin secretion in this species. Baboons are 98 % genetically similar to humans and therefore represent the ideal model to study metabolic diseases and new treatments that could eventually be employed in humans.   My laboratory is also interested in studying novel mechanisms of insulin resistance and defective insulin secretion in humans affected by obesity and type 2 diabetes, employing an in-vivo physiology approaches coupled with subcellular proteomics and genomics.


 

Perani D, Garibotto V, Moresco RM, Ortelli P, Corbo M, Fazio F, Folli F.
PET evidence of central GABAergic changes in stiff-person syndrome.
Mov Disord. 2007 May 15;22(7):1030-3.
PMID: 17575583

Folli F, Pontiroli AE, Schwesinger WH.
Metabolic aspects of bariatric surgery.
Med Clin North Am. 2007 May;91(3):393-414, x. Review.
PMID: 17509385

Prudente S, Flex E, Morini E, Turchi F, Capponi D, De Cosmo S, Tassi V, Guida V, Avogaro A, Folli F, Maiani F, Frittitta L, Dallapiccola B, Trischitta V.
A functional variant of the adipocyte glycerol channel aquaporin 7 gene is associated with obesity and related metabolic abnormalities.
Diabetes. 2007 May;56(5):1468-74. Epub 2007 Mar 9.
PMID: 17351148

Pontiroli AE, Pizzocri P, Paroni R, Folli F.
Sympathetic overactivity, endothelial dysfunction, inflammation, and metabolic abnormalities cluster in grade III (World Health Organization) obesity: reversal through sustained weight loss obtained with laparoscopic adjustable gastric banding.
Diabetes Care. 2006 Dec;29(12):2735-8. No abstract available.
PMID: 17130217

Folli F, Galimberti G, Pastore M, Davalli AM, Bosi E.
Paraneoplastic insulin resistance syndrome in advanced aggressive fibromatosis (desmoid tumor) treated by imatinib mesylate.
Diabetes Care. 2006 Sep;29(9):2178-80. No abstract available.
PMID: 16936177

Velloso LA, Folli F, Perego L, Saad MJ.
The multi-faceted cross-talk between the insulin and angiotensin II signaling systems.
Diabetes Metab Res Rev. 2006 Mar-Apr;22(2):98-107. Review.
PMID: 16389635

Scavini M, Pontiroli AE, Folli F.
Asymptomatic hyperinsulinemic hypoglycemia after gastric banding.
N Engl J Med. 2005 Dec 29;353(26):2822-3. No abstract available.
PMID: 16382076

Finzi G, Davalli A, Placidi C, Usellini L, La Rosa S, Folli F, Capella C.
Morphological and ultrastructural features of human islet grafts performed in diabetic nude mice.
Ultrastruct Pathol. 2005 Nov-Dec;29(6):525-33.
PMID: 16316953

Pontiroli AE, Folli F, Paganelli M, Micheletto G, Pizzocri P, Vedani P, Luisi F, Perego L, Morabito A, Bressani Doldi S.
Laparoscopic gastric banding prevents type 2 diabetes and arterial hypertension and induces their remission in morbid obesity: a 4-year case-controlled study.
Diabetes Care. 2005 Nov;28(11):2703-9.
PMID: 16249543

Fiorina P, Folli F, Ferrero E, Orsenigo E, Finzi G, Mazzolari G, Placidi C, Perego L, La Rosa S, Melandri M, Monti L, Capella C, D'Angelo A, Staudacher C, Secchi A.
Morphological and functional differences in haemostatic axis between kidney transplanted and end-stage renal disease patients.
Transpl Int. 2005 Sep;18(9):1036-47.
PMID: 16101724

Cardellini M, Perego L, D'Adamo M, Marini MA, Procopio C, Hribal ML, Andreozzi F, Frontoni S, Giacomelli M, Paganelli M, Pontiroli AE, Lauro R, Folli F, Sesti G.
C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance.
Diabetes Care. 2005 Aug;28(8):2007-12.
PMID: 16043746

Sesti G, Perego L, Cardellini M, Andreozzi F, Ricasoli C, Vedani P, Guzzi V, Marchi M, Paganelli M, Ferla G, Pontiroli AE, Hribal ML, Folli F.
Impact of common polymorphisms in candidate genes for insulin resistance and obesity on weight loss of morbidly obese subjects after laparoscopic adjustable gastric banding and hypocaloric diet.
J Clin Endocrinol Metab. 2005 Sep;90(9):5064-9. Epub 2005 Jun 28. Erratum in: J Clin Endocrinol Metab. 2005 Oct;90(10):5810.
PMID: 15985484

Fiorina P, Gremizzi C, Maffi P, Caldara R, Tavano D, Monti L, Socci C, Folli F, Fazio F, Astorri E, Del Maschio A, Secchi A.
Islet transplantation is associated with an improvement of cardiovascular function in type 1 diabetic kidney transplant patients.
Diabetes Care. 2005 Jun;28(6):1358-65.
PMID: 15920052

Fiorina P, Venturini M, Folli F, Losio C, Maffi P, Placidi C, La Rosa S, Orsenigo E, Socci C, Capella C, Del Maschio A, Secchi A.
Natural history of kidney graft survival, hypertrophy, and vascular function in end-stage renal disease type 1 diabetic kidney-transplanted patients: beneficial impact of pancreas and successful islet cotransplantation.
Diabetes Care. 2005 Jun;28(6):1303-10.
PMID: 15920043

Perego L, Pizzocri P, Corradi D, Maisano F, Paganelli M, Fiorina P, Barbieri M, Morabito A, Paolisso G, Folli F, Pontiroli AE.
Circulating leptin correlates with left ventricular mass in morbid (grade III) obesity before and after weight loss induced by bariatric surgery: a potential role for leptin in mediating human left ventricular hypertrophy.
J Clin Endocrinol Metab. 2005 Jul;90(7):4087-93. Epub 2005 Apr 26.
PMID: 15855267

Ueno M, Carvalheira JB, Tambascia RC, Bezerra RM, Amaral ME, Carneiro EM, Folli F, Franchini KG, Saad MJ.
Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway.
Diabetologia. 2005 Mar;48(3):506-18. Epub 2005 Feb 4.
PMID: 15692808

Veronelli A, Laneri M, Ranieri R, Koprivec D, Vardaro D, Paganelli M, Folli F, Pontiroli AE.
White blood cells in obesity and diabetes: effects of weight loss and normalization of glucose metabolism.
Diabetes Care. 2004 Oct;27(10):2501-2. No abstract available.
PMID: 15451926

Fiorina P, Folli F, D'Angelo A, Finzi G, Pellegatta F, Guzzi V, Fedeli C, Della Valle P, Usellini L, Placidi C, Bifari F, Belloni D, Ferrero E, Capella C, Secchi A.
Normalization of multiple hemostatic abnormalities in uremic type 1 diabetic patients after kidney-pancreas transplantation.
Diabetes. 2004 Sep;53(9):2291-300.
PMID: 15331538

Fiorina P, Corradi D, Pinelli S, Maestri R, Lagrasta C, Buscaglia M, Davalli A, Folli F, Astorri E.
Apoptotic/mytogenic pathways during human heart development.
Int J Cardiol. 2004 Sep;96(3):409-17.
PMID: 15301895

D'Adamo M, Perego L, Cardellini M, Marini MA, Frontoni S, Andreozzi F, Sciacqua A, Lauro D, Sbraccia P, Federici M, Paganelli M, Pontiroli AE, Lauro R, Perticone F, Folli F, Sesti G.
The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.
Diabetes. 2004 Jul;53(7):1905-10.
PMID: 15220218

Svegliati-Baroni G, Ridolfi F, Caradonna Z, Alvaro D, Marzioni M, Saccomanno S, Candelaresi C, Trozzi L, Macarri G, Benedetti A, Folli F.
Regulation of ERK/JNK/p70S6K in two rat models of liver injury and fibrosis.
J Hepatol. 2003 Oct;39(4):528-37.
PMID: 12971962

Fiorina P, Folli F, Zerbini G, Maffi P, Gremizzi C, Di Carlo V, Socci C, Bertuzzi F, Kashgarian M, Secchi A.
Islet transplantation is associated with improvement of renal function among uremic patients with type I diabetes mellitus and kidney transplants.
J Am Soc Nephrol. 2003 Aug;14(8):2150-8.
PMID: 12874470

Hribal ML, Perego L, Lovari S, Andreozzi F, Menghini R, Perego C, Finzi G, Usellini L, Placidi C, Capella C, Guzzi V, Lauro D, Bertuzzi F, Davalli A, Pozza G, Pontiroli A, Federici M, Lauro R, Brunetti A, Folli F, Sesti G.
Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN beta cell line and human islets of Langerhans.
FASEB J. 2003 Jul;17(10):1340-2. Epub 2003 May 8.
PMID: 12738810

Fiorina P, Folli F, Maffi P, Placidi C, Venturini M, Finzi G, Bertuzzi F, Davalli A, D'Angelo A, Socci C, Gremizzi C, Orsenigo E, La Rosa S, Ponzoni M, Cardillo M, Scalamogna M, Del Maschio A, Capella C, Di Carlo V, Secchi A.
Islet transplantation improves vascular diabetic complications in patients with diabetes who underwent kidney transplantation: a comparison between kidney-pancreas and kidney-alone transplantation.
Transplantation. 2003 Apr 27;75(8):1296-301.
PMID: 12717219

Carvalheira JB, Ribeiro EB, Folli F, Velloso LA, Saad MJ.
Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver.
Biol Chem. 2003 Jan;384(1):151-9.
PMID: 12674509

Fiorina P, Folli F, Bertuzzi F, Maffi P, Finzi G, Venturini M, Socci C, Davalli A, Orsenigo E, Monti L, Falqui L, Uccella S, La Rosa S, Usellini L, Properzi G, Di Carlo V, Del Maschio A, Capella C, Secchi A.
Long-term beneficial effect of islet transplantation on diabetic macro-/microangiopathy in type 1 diabetic kidney-transplanted patients.
Diabetes Care. 2003 Apr;26(4):1129-36.
PMID: 12663585

Polastri L, Galbiati F, Folli F, Davalli AM.
Effects of carboxypeptidase E overexpression on insulin mRNA levels, regulated insulin secretion, and proinsulin processing of pituitary GH3 cells transfected with a furin-cleavable human proinsulin cDNA.
Cell Transplant. 2002;11(8):803-11.
PMID: 12588113

Pontiroli AE, Pizzocri P, Giacomelli M, Marchi M, Vedani P, Cucchi E, Orena C, Folli F, Paganelli M, Ferla G.
Ultrasound measurement of visceral and subcutaneous fat in morbidly obese patients before and after laparoscopic adjustable gastric banding: comparison with computerized tomography and with anthropometric measurements.
Obes Surg. 2002 Oct;12(5):648-51.
PMID: 12448386

Folli F, Perego L, Ponzoni M, Girardi AM, Bosi E, Ferreri AJ, Bellone M, Sabbadini MG, Vicari AM, Trusolino L.
Autoantibodies against a 72-kDa ductal cell membrane glycoprotein in a patient affected by Sjogren's syndrome and gastric MALT lymphoma.
Ann Hematol. 2002 Oct;81(10):597-602. Epub 2002 Sep 24. Erratum in: Ann Hematol. 2003 Mar;82(3):203.
PMID: 12424543

Galbiati F, Polastri L, Gregori S, Freschi M, Casorati M, Cavallaro U, Fiorina P, Bertuzzi F, Zerbi A, Pozza G, Adorini L, Folli F, Christofori G, Davalli AM.
Antitumorigenic and antiinsulinogenic effects of calcitriol on insulinoma cells and solid beta-cell tumors.
Endocrinology. 2002 Oct;143(10):4018-30.
PMID: 12239113

Pontiroli AE, Pizzocri P, Folli F.
Plasma leptin levels and coronary heart disease.
Circulation. 2002 Aug 27;106(9):e42; author reply e42. No abstract available.
PMID: 12196352

Pontiroli AE, Pizzocri P, Librenti MC, Vedani P, Marchi M, Cucchi E, Orena C, Paganelli M, Giacomelli M, Ferla G, Folli F.
Laparoscopic adjustable gastric banding for the treatment of morbid (grade 3) obesity and its metabolic complications: a three-year study.
J Clin Endocrinol Metab. 2002 Aug;87(8):3555-61.
PMID: 12161474

Alvaro D, Alpini G, Onori P, Franchitto A, Glaser SS, Le Sage G, Folli F, Attili AF, Gaudio E.
Alfa and beta estrogen receptors and the biliary tree.
Mol Cell Endocrinol. 2002 Jul 31;193(1-2):105-8. Review.
PMID: 12161009

Alvaro D, Onori P, Metalli VD, Svegliati-Baroni G, Folli F, Franchitto A, Alpini G, Mancino MG, Attili AF, Gaudio E.
Intracellular pathways mediating estrogen-induced cholangiocyte proliferation in the rat.
Hepatology. 2002 Aug;36(2):297-304.
PMID: 12143037

Perego L, Previtali SC, Nemni R, Longhi R, Carandente O, Saibene A, Sciolla R, Villa A, Gai P, Panzeri C, Dell'Antonio G, Quattrini A, Folli F.
Autoantibodies to amphiphysin I and amphiphysin II in a patient with sensory-motor neuropathy.
Eur Neurol. 2002;47(4):196-200.
PMID: 12037431

Ponzoni M, Patriarca C, Arrigoni G, Gianelli U, Vicari A, Folli F.
Extramedullary myeloid cell tumor/granulocytic sarcoma with predilection for serosal surfaces.
Haematologica. 2002 Mar;87(3):ECR09. No abstract available.
PMID: 11869955

Chiellini C, Bertacca A, Novelli SE, Gorgun CZ, Ciccarone A, Giordano A, Xu H, Soukas A, Costa M, Gandini D, Dimitri R, Bottone P, Cecchetti P, Pardini E, Perego L, Navalesi R, Folli F, Benzi L, Cinti S, Friedman JM, Hotamisligil GS, Maffei M.
Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha.
J Cell Physiol. 2002 Feb;190(2):251-8.
PMID: 11807829

Pizzocri P, Koprivec D, Folli F, Vedani P, Marchi M, Paganelli M, Pontiroli AE.
Changes in lipid levels with percent of weight loss in morbid obesity.
Obes Surg. 2001 Oct;11(5):649-50. No abstract available.
PMID: 11594114

Pellegatta F, Radaelli A, Heltai S, Yan L, Chierchia SL, Folli F.
Evidence for the involvement of phosphatidylinositol 3-kinase in fMLP-stimulated neutrophil adhesion to ICAM-1-transfected cells.
J Cardiovasc Pharmacol. 2001 Jun;37(6):751-61.
PMID: 11392472

Federici M, Hribal M, Perego L, Ranalli M, Caradonna Z, Perego C, Usellini L, Nano R, Bonini P, Bertuzzi F, Marlier LN, Davalli AM, Carandente O, Pontiroli AE, Melino G, Marchetti P, Lauro R, Sesti G, Folli F.
High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program.
Diabetes. 2001 Jun;50(6):1290-301.
PMID: 11375329

Davalli AM, Galbiati F, Bertuzzi F, Polastri L, Pontiroli AE, Perego L, Freschi M, Pozza G, Folli F, Meoni C.
Insulin-secreting pituitary GH3 cells: a potential beta-cell surrogate for diabetes cell therapy.
Cell Transplant. 2000 Nov-Dec;9(6):841-51.
PMID: 11202570

Meoni C, Bertuzzi F, Pontiroli AE, Falqui L, Monaco L, Soria M, Arcelloni C, Paroni R, Foglieni C, Polastri L, Galbiati F, Folli F, Davalli AM.
Development and characterization of pituitary GH3 cell clones stably transfected with a human proinsulin cDNA.
Cell Transplant. 2000 Nov-Dec;9(6):829-40.
PMID: 11202569

Alvaro D, Alpini G, Onori P, Perego L, Svegliata Baroni G, Franchitto A, Baiocchi L, Glaser SS, Le Sage G, Folli F, Gaudio E.
Estrogens stimulate proliferation of intrahepatic biliary epithelium in rats.
Gastroenterology. 2000 Dec;119(6):1681-91.
PMID: 11113090

Svegliati-Baroni G, Ridolfi F, Di Sario A, Casini A, Marucci L, Gaggiotti G, Orlandoni P, Macarri G, Perego L, Benedetti A, Folli F.
Insulin and insulin-like growth factor-1 stimulate proliferation and type I collagen accumulation by human hepatic stellate cells: differential effects on signal transduction pathways.
Hepatology. 1999 Jun;29(6):1743-51.
PMID: 10347117

Folli F, Saad MJ, Velloso L, Hansen H, Carandente O, Feener EP, Kahn CR.
Crosstalk between insulin and angiotensin II signalling systems.
Exp Clin Endocrinol Diabetes. 1999;107(2):133-9. Review.
PMID: 10320054

Pigazzi A, Heydrick S, Folli F, Benoit S, Michelson A, Loscalzo J.
Nitric oxide inhibits thrombin receptor-activating peptide-induced phosphoinositide 3-kinase activity in human platelets.
J Biol Chem. 1999 May 14;274(20):14368-75.
PMID: 10318860

Pontiroli AE, Folli F.
Is it worth treating diabetes? Lessons from the UKPDS. United Kingdom Prospective Diabetes Study.
Acta Diabetol. 1998 Dec;35(4):170-1. No abstract available.
PMID: 9934813

Velloso LA, Carvalho CR, Rojas FA, Folli F, Saad MJ.
Insulin signalling in heart involves insulin receptor substrates-1 and -2, activation of phosphatidylinositol 3-kinase and the JAK 2-growth related pathway.
Cardiovasc Res. 1998 Oct;40(1):96-102.
PMID: 9876321

Folli F.
Stiff man syndrome, 40 years later.
J Neurol Neurosurg Psychiatry. 1998 Nov;65(5):618. No abstract available.
PMID: 9810927

Manfredi PL, Herskovitz S, Folli F, Pigazzi A, Swerdlow ML.
Spinal epidural abscess: treatment options.
Eur Neurol. 1998 Jul;40(1):58-60. No abstract available.
PMID: 9729116

Vicari AM, Ponzoni M, Alberetto M, Martani C, Pontiroli AE, Folli F.
Erythrocytosis in a patient with chronic obstructive pulmonary disease.
Haematologica. 1998 Feb;83(2):183-6.
PMID: 9549929

Vicari AM, Ciceri F, Folli F, Lanzi R, Colombo B, Comi G, Camba L.
Acute promyelocytic leukemia following mitoxantrone as single agent for the treatment of multiple sclerosis.
Leukemia. 1998 Mar;12(3):441-2. No abstract available.
PMID: 9529141

Gerra G, Zaimovic A, Giucastro G, Folli F, Maestri D, Tessoni A, Avanzini P, Caccavari R, Bernasconi S, Brambilla F.
Neurotransmitter-hormonal responses to psychological stress in peripubertal subjects: relationship to aggressive behavior.
Life Sci. 1998;62(7):617-25.
PMID: 9472721

Folli F, Kahn CR, Hansen H, Bouchie JL, Feener EP.
Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.
J Clin Invest. 1997 Nov 1;100(9):2158-69.
PMID: 9410892

Folli F, Alvaro D, Gigliozzi A, Bassotti C, Kahn CR, Pontiroli AE, Capocaccia L, Jezequel AM, Benedetti A.
Regulation of endocytic-transcytotic pathways and bile secretion by phosphatidylinositol 3-kinase in rats.
Gastroenterology. 1997 Sep;113(3):954-65.
PMID: 9287989

Folli F, Ponzoni M, Vicari AM.
Paraneoplastic autoimmune xerostomia.
Ann Intern Med. 1997 Jul 15;127(2):167-8. No abstract available.
PMID: 9230018

Velloso LA, Folli F, Sun XJ, White MF, Saad MJ, Kahn CR.
Cross-talk between the insulin and angiotensin signaling systems.
Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12490-5.
PMID: 8901609

Folli F, Ghidella S, Bonfanti L, Kahn CR, Merighi A.
The early intracellular signaling pathway for the insulin/insulin-like growth factor receptor family in the mammalian central nervous system.
Mol Neurobiol. 1996 Oct;13(2):155-83. Review.
PMID: 8938649

Vicari AM, Taglietti MV, Pellegatta F, Spotti D, Melandri M, Galli L, Ronchi P, Folli F.
Deranged platelet calcium homeostasis in diabetic patients with end-stage renal failure. A possible link to increased cardiovascular mortality?
Diabetes Care. 1996 Oct;19(10):1062-6.
PMID: 8886550

Folli F, Saad MJ, Kahn CR.
Insulin receptor/IRS-1/PI 3-kinase signaling system in corticosteroid-induced insulin resistance.
Acta Diabetol. 1996 Sep;33(3):185-92. Review. No abstract available.
PMID: 8904923

Goldfine AB, Simonson DC, Folli F, Patti ME, Kahn CR.
In vivo and in vitro studies of vanadate in human and rodent diabetes mellitus.
Mol Cell Biochem. 1995 Dec 6-20;153(1-2):217-31. Review.
PMID: 8927042

Goldfine AB, Simonson DC, Folli F, Patti ME, Kahn CR.
Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies.
J Clin Endocrinol Metab. 1995 Nov;80(11):3311-20.
PMID: 7593444

Saad MJ, Folli F, Kahn CR.
Insulin and dexamethasone regulate insulin receptors, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in Fao hepatoma cells.
Endocrinology. 1995 Apr;136(4):1579-88.
PMID: 7895667

Folli F, Bonfanti L, Renard E, Kahn CR, Merighi A.
Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system.
J Neurosci. 1994 Nov;14(11 Pt 1):6412-22.
PMID: 7965046

Vicari AM, Monzani ML, Pellegatta F, Ronchi P, Galli L, Folli F.
Platelet calcium homeostasis is abnormal in patients with severe arteriosclerosis.
Arterioscler Thromb. 1994 Sep;14(9):1420-4.
PMID: 8068602

Saad MJ, Folli F, Araki E, Hashimoto N, Csermely P, Kahn CR.
Regulation of insulin receptor, insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-F442A adipocytes. Effects of differentiation, insulin, and dexamethasone.
Mol Endocrinol. 1994 May;8(5):545-57.
PMID: 7520127

De Camilli P, Thomas A, Cofiell R, Folli F, Lichte B, Piccolo G, Meinck HM, Austoni M, Fassetta G, Bottazzo G, et al.
The synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen of Stiff-Man syndrome with breast cancer.
J Exp Med. 1993 Dec 1;178(6):2219-23.
PMID: 8245793

Saad MJ, Folli F, Kahn JA, Kahn CR.
Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats.
J Clin Invest. 1993 Oct;92(4):2065-72.
PMID: 7691892

Folli F, Saad MJ, Backer JM, Kahn CR.
Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus.
J Clin Invest. 1993 Oct;92(4):1787-94.
PMID: 7691886

Folli F, Solimena M, Cofiell R, Austoni M, Tallini G, Fassetta G, Bates D, Cartlidge N, Bottazzo GF, Piccolo G, et al.
Autoantibodies to a 128-kd synaptic protein in three women with the stiff-man syndrome and breast cancer.
N Engl J Med. 1993 Feb 25;328(8):546-51.
PMID: 8381208

Pellegatta F, Folli F, Ronchi P, Caspani L, Galli L, Vicari AM.
Deranged platelet calcium homeostasis in poorly controlled IDDM patients.
Diabetes Care. 1993 Jan;16(1):178-83.
PMID: 8422772

Kahn CR, White MF, Shoelson SE, Backer JM, Araki E, Cheatham B, Csermely P, Folli F, Goldstein BJ, Huertas P, et al.
The insulin receptor and its substrate: molecular determinants of early events in insulin action.
Recent Prog Horm Res. 1993;48:291-339. Review. No abstract available.
PMID: 7680139

Kahn CR, Folli F.
Molecular determinants of insulin action.
Horm Res. 1993;39 Suppl 3:93-101. Review.
PMID: 7505252

Folli F, Saad MJ, Backer JM, Kahn CR.
Insulin stimulation of phosphatidylinositol 3-kinase activity and association with insulin receptor substrate 1 in liver and muscle of the intact rat.
J Biol Chem. 1992 Nov 5;267(31):22171-7.
PMID: 1385396

Reetz A, Solimena M, Matteoli M, Folli F, Takei K, De Camilli P.
GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.
EMBO J. 1991 May;10(5):1275-84.
PMID: 2022191

Baekkeskov S, Aanstoot HJ, Christgau S, Reetz A, Solimena M, Cascalho M, Folli F, Richter-Olesen H, De Camilli P.
Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase.
Nature. 1990 Sep 13;347(6289):151-6. Erratum in: Nature 1990 Oct 25;347(6295):782. Camilli, PD [corrected to De Camilli, P].
PMID: 1697648

Solimena M, Folli F, Aparisi R, Pozza G, De Camilli P.
Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome.
N Engl J Med. 1990 May 31;322(22):1555-60.
PMID: 2135382