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Jean X. Jiang,
Professor; Ph.D., State University of New York at Stony Brook, 1991.
Telephone: (210) 567-3796 E-mail: jiangj@uthscsa.edu www: http://www.biochem.uthscsa.edu/~jiang Gap junction mediated cell-to-cell communication and intercellular signaling mechanisms. Molecular characterization of amino acid transporters. |
Banks
EA, Yu XS, Shi Q, Jiang JX.
Promotion of lens epithelial-fiber differentiation by the C-terminus
of connexin 45.6 a role independent of gap junction communication.
J Cell Sci. 2007 Oct 15;120(Pt 20):3602-12. Epub 2007 Sep 25.
PMID: 17895360
Jiang
JX, Siller-Jackson AJ, Burra S.
Roles of gap junctions and hemichannels in bone cell functions and
in signal transmission of mechanical stress.
Front Biosci. 2007 Jan 1;12:1450-62. Review.
PMID: 17127393
Gluhak-Heinrich
J, Gu S, Pavlin D, Jiang JX.
Mechanical loading stimulates expression of connexin 43 in alveolar
bone cells in the tooth movement model.
Cell Commun Adhes. 2006 Jan-Apr;13(1-2):115-25.
PMID: 16613785
Jiang
JX, Gu S.
Gap junction- and hemichannel-independent actions of connexins.
Biochim Biophys Acta. 2005 Jun 10;1711(2):208-14. Epub 2004
Oct 22. Review.
PMID: 15955305 [PubMed - indexed for MEDLINE]
Gu
S, Villegas CJ, Jiang JX.
Differential regulation of amino acid transporter SNAT3 by insulin
in hepatocytes.
J Biol Chem. 2005 Jul 15;280(28):26055-62. Epub 2005 May 16.
PMID: 15899884 [PubMed - indexed for MEDLINE]
Cherian
PP, Siller-Jackson AJ, Gu S, Wang X, Bonewald LF, Sprague E, Jiang JX.
Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel
mechanism for the release of prostaglandin.
Mol Biol Cell. 2005 Jul;16(7):3100-6. Epub 2005 Apr 20.
PMID: 15843434
Yu
XS, Yin X, Lafer EM, Jiang JX.
Developmental regulation of the direct interaction between the intracellular
loop of connexin 45.6 and the C terminus of major intrinsic protein (aquaporin-0).
J Biol Chem. 2005 Jun 10;280(23):22081-90. Epub 2005 Mar 31.
PMID: 15802270 [PubMed - indexed for MEDLINE]
Yu
XS, Jiang JX.
Interaction of major intrinsic protein (aquaporin-0) with fiber connexins
in lens development.
J Cell Sci. 2004 Feb 29;117(Pt 6):871-80. Epub 2004 Feb 03.
PMID: 14762116 [PubMed - indexed for MEDLINE]
Jiang
JX, Cherian PP.
Hemichannels formed by connexin 43 play an important role in the release
of prostaglandin E(2) by osteocytes in response to mechanical strain.
Cell Commun Adhes. 2003 Jul-Dec;10(4-6):259-64.
PMID: 14681026 [PubMed - indexed for MEDLINE]
Cherian
PP, Cheng B, Gu S, Sprague E, Bonewald LF, Jiang JX.
Effects of mechanical strain on the function of Gap junctions in osteocytes
are mediated through the prostaglandin EP2 receptor.
J Biol Chem. 2003 Oct 31;278(44):43146-56. Epub 2003 Aug 25.
PMID: 12939279 [PubMed - indexed for MEDLINE]
Gu
S, Yu XS, Yin X, Jiang JX.
Stimulation of lens cell differentiation by gap junction protein connexin
45.6.
Invest Ophthalmol Vis Sci. 2003 May;44(5):2103-11.
PMID: 12714649 [PubMed - indexed for MEDLINE]
Gu
S, Langlais P, Liu F, Jiang JX.
Mouse system-N amino acid transporter, mNAT3, expressed in hepatocytes
and regulated by insulin-activated and phosphoinositide 3-kinase-dependent
signalling.
Biochem J. 2003 May 1;371(Pt 3):721-31.
PMID: 12537539 [PubMed - indexed for MEDLINE]
Choi
D, Oh HJ, Chang UJ, Koo SK, Jiang JX, Hwang SY, Lee JD, Yeoh GC, Shin HS,
Lee JS, Oh B.
In vivo differentiation of mouse embryonic stem cells into hepatocytes.
Cell Transplant. 2002;11(4):359-68.
PMID: 12162376 [PubMed - indexed for MEDLINE]
Yin
X, Gu S, Jiang JX.
Regulation of lens connexin 45.6 by apoptotic protease, caspase-3.
Cell Commun Adhes. 2001;8(4-6):373-6.
PMID: 12064621 [PubMed - indexed for MEDLINE]
Jiang
JX, Cheng B.
Mechanical stimulation of gap junctions in bone osteocytes is mediated
by prostaglandin E2.
Cell Commun Adhes. 2001;8(4-6):283-8.
PMID: 12064603 [PubMed - indexed for MEDLINE]
Cheng
B, Kato Y, Zhao S, Luo J, Sprague E, Bonewald LF, Jiang JX.
PGE(2) is essential for gap junction-mediated intercellular communication
between osteocyte-like MLO-Y4 cells in response to mechanical strain.
Endocrinology. 2001 Aug;142(8):3464-73.
PMID: 11459792 [PubMed - indexed for MEDLINE]
Yin
X, Gu S, Jiang JX.
The development-associated cleavage of lens connexin 45.6 by caspase-3-like
protease is regulated by casein kinase II-mediated phosphorylation.
J Biol Chem. 2001 Sep 14;276(37):34567-72. Epub 2001 Jul 11.
PMID: 11448971 [PubMed - indexed for MEDLINE]
Gu
S, Adan-Rice D, Leach RJ, Jiang JX.
A novel human amino acid transporter, hNAT3: cDNA cloning, chromosomal
mapping, genomic structure, expression, and functional characterization.
Genomics. 2001 Jun 15;74(3):262-72.
PMID: 11414754 [PubMed - indexed for MEDLINE]
Gu
S, Roderick HL, Camacho P, Jiang JX.
Characterization of an N-system amino acid transporter expressed in
retina and its involvement in glutamine transport.
J Biol Chem. 2001 Jun 29;276(26):24137-44. Epub 2001 Apr 26.
PMID: 11325958 [PubMed - indexed for MEDLINE]
Jiang
JX.
Use of retroviruses to express connexins.
Methods Mol Biol. 2001;154:159-74. No abstract available.
PMID: 11218647 [PubMed - indexed for MEDLINE]
Cheng
B, Zhao S, Luo J, Sprague E, Bonewald LF, Jiang JX.
Expression of functional gap junctions and regulation by fluid flow
in osteocyte-like MLO-Y4 cells.
J Bone Miner Res. 2001 Feb;16(2):249-59.
PMID: 11204425 [PubMed - indexed for MEDLINE]
Gu
S, Roderick HL, Camacho P, Jiang JX.
Identification and characterization of an amino acid transporter expressed
differentially in liver.
Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3230-5.
PMID: 10716701 [PubMed - indexed for MEDLINE]
Yin
X, Jedrzejewski PT, Jiang JX.
Casein kinase II phosphorylates lens connexin 45.6 and is involved
in its degradation.
J Biol Chem. 2000 Mar 10;275(10):6850-6.
PMID: 10702244 [PubMed - indexed for MEDLINE]
He
DS, Jiang JX, Taffet SM, Burt JM.
Formation of heteromeric gap junction channels by connexins 40 and
43 in vascular smooth muscle cells.
Proc Natl Acad Sci U S A. 1999 May 25;96(11):6495-500.
PMID: 10339616 [PubMed - indexed for MEDLINE]
Jiang
JX, Goodenough DA.
Phosphorylation of lens-fiber connexins in lens organ cultures.
Eur J Biochem. 1998 Jul 1;255(1):37-44.
PMID: 9692898 [PubMed - indexed for MEDLINE]
Jiang
JX, Goodenough DA.
Retroviral expression of connexins in embryonic chick lens.
Invest Ophthalmol Vis Sci. 1998 Mar;39(3):537-43.
PMID: 9501864 [PubMed - indexed for MEDLINE]
Jiang
JX, Goodenough DA.
Heteromeric connexons in lens gap junction channels.
Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1287-91.
PMID: 8577756 [PubMed - indexed for MEDLINE]
Jiang
JX, White TW, Goodenough DA.
Changes in connexin expression and distribution during chick lens development.
Dev Biol. 1995 Apr;168(2):649-61.
PMID: 7729595 [PubMed - indexed for MEDLINE]
Jiang
JX, White TW, Goodenough DA, Paul DL.
Molecular cloning and functional characterization of chick lens fiber
connexin 45.6.
Mol Biol Cell. 1994 Mar;5(3):363-73.
PMID: 8049527 [PubMed - indexed for MEDLINE]
Jiang
JX, Paul DL, Goodenough DA.
Posttranslational phosphorylation of lens fiber connexin46: a slow
occurrence.
Invest Ophthalmol Vis Sci. 1993 Dec;34(13):3558-65.
PMID: 8258513 [PubMed - indexed for MEDLINE]
London
E, Ulbrandt ND, Tortorella D, Jiang JX, Abrams FS.
Insights into membrane protein folding and translocation from the behavior
of bacterial toxins: models for membrane translocation.
Soc Gen Physiol Ser. 1993;48:45-61. Review. No abstract available.
PMID: 8503054 [PubMed - indexed for MEDLINE]
Jiang
JX, Chung LA, London E.
Self-translocation of diphtheria toxin across model membranes.
J Biol Chem. 1991 Dec 15;266(35):24003-10.
PMID: 1721061 [PubMed - indexed for MEDLINE]
Jiang
JX, Abrams FS, London E.
Folding changes in membrane-inserted diphtheria toxin that may play
important roles in its translocation.
Biochemistry. 1991 Apr 23;30(16):3857-64.
PMID: 1850289 [PubMed - indexed for MEDLINE]
Jiang
JX, London E.
Involvement of denaturation-like changes in Pseudomonas exotoxin a
hydrophobicity and membrane penetration determined by characterization
of pH and thermal transitions. Roles of two distinct conformationally altered
states.
J Biol Chem. 1990 May 25;265(15):8636-41.
PMID: 2111323 [PubMed - indexed for MEDLINE]