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Nicolas Musi, Assistant
Professor; M.D., Universidad Anahuac, Mexico City, 1994.
Telephone: (210) 567-6691 E-mail: musi@uthscsa.edu |
Fernandez
M, Triplitt C, Wajcberg E, Sriwijilkamol AA, Musi N, Cusi K, Defronzo R,
Cersosimo E.
Addition of Pioglitazone and Ramipril to Intensive Insulin Therapy
in Type 2 Diabetic Patients Improves Vascular Dysfunction by Different
Mechanisms.
Diabetes Care. 2007 Oct 1; [Epub ahead of print]
PMID: 17909084
Wang
L, Balas B, Christ-Roberts CY, Kim RY, Ramos FJ, Kikani CK, Li C, Deng
C, Reyna S, Musi N, Dong LQ, DeFronzo RA, Liu F.
Peripheral disruption of the Grb10 gene enhances insulin signaling
and sensitivity in vivo.
Mol Cell Biol. 2007 Sep;27(18):6497-505. Epub 2007 Jul 9.
PMID: 17620412
Bajaj
M, Suraamornkul S, Hardies LJ, Glass L, Musi N, DeFronzo RA.
Effects of peroxisome proliferator-activated receptor (PPAR)-alpha
and PPAR-gamma agonists on glucose and lipid metabolism in patients with
type 2 diabetes mellitus.
Diabetologia. 2007 Aug;50(8):1723-31. Epub 2007 May 23.
PMID: 17520238
Laine
PS, Schwartz EA, Wang Y, Zhang WY, Karnik SK, Musi N, Reaven PD.
Palmitic acid induces IP-10 expression in human macrophages via NF-kappaB
activation.
Biochem Biophys Res Commun. 2007 Jun 22;358(1):150-5. Epub 2007
Apr 20.
PMID: 17467667
Luptak
I, Shen M, He H, Hirshman MF, Musi N, Goodyear LJ, Yan J, Wakimoto H, Morita
H, Arad M, Seidman CE, Seidman JG, Ingwall JS, Balschi JA, Tian R.
Aberrant activation of AMP-activated protein kinase remodels metabolic
network in favor of cardiac glycogen storage.
J Clin Invest. 2007 May;117(5):1432-9. Epub 2007 Apr 12.
PMID: 17431505
Wajcberg
E, Sriwijitkamol A, Musi N, DeFronzo RA, Cersosimo E.
Relationship between vascular reactivity and lipids in Mexican-Americans
with type 2 diabetes treated with pioglitazone.
J Clin Endocrinol Metab. 2007 Apr;92(4):1256-62. Epub 2007 Jan
23.
PMID: 17244785
Sriwijitkamol
A, Coletta DK, Wajcberg E, Balbontin GB, Reyna SM, Barrientes J, Eagan
PA, Jenkinson CP, Cersosimo E, DeFronzo RA, Sakamoto K, Musi N.
Effect of acute exercise on AMPK signaling in skeletal muscle of subjects
with type 2 diabetes: a time-course and dose-response study.
Diabetes. 2007 Mar;56(3):836-48.
PMID: 17327455
Lee
MJ, Feliers D, Mariappan MM, Sataranatarajan K, Mahimainathan L, Musi N,
Foretz M, Viollet B, Weinberg JM, Choudhury GG, Kasinath BS.
A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy.
Am J Physiol Renal Physiol. 2007 Feb;292(2):F617-27. Epub 2006
Oct 3.
PMID: 17018841
Schimmack
G, Defronzo RA, Musi N.
AMP-activated protein kinase: Role in metabolism and therapeutic implications.
Diabetes Obes Metab. 2006 Nov;8(6):591-602. Review.
PMID: 17026483
Kuhl
JE, Ruderman NB, Musi N, Goodyear LJ, Patti ME, Crunkhorn S, Dronamraju
D, Thorell A, Nygren J, Ljungkvist O, Degerblad M, Stahle A, Brismar TB,
Andersen KL, Saha AK, Efendic S, Bavenholm PN.
Exercise training decreases the concentration of malonyl-CoA and increases
the expression and activity of malonyl-CoA decarboxylase in human muscle.
Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1296-303. Epub
2006 Jan 24.
PMID: 16434556
Sriwijitkamol
A, Ivy JL, Christ-Roberts C, DeFronzo RA, Mandarino LJ, Musi N.
LKB1-AMPK signaling in muscle from obese insulin-resistant Zucker rats
and effects of training.
Am J Physiol Endocrinol Metab. 2006 May;290(5):E925-32. Epub
2005 Dec 13.
PMID: 16352671
Sriwijitkamol
A, Christ-Roberts C, Berria R, Eagan P, Pratipanawatr T, DeFronzo RA, Mandarino
LJ, Musi N.
Reduced skeletal muscle inhibitor of kappaB beta content is associated
with insulin resistance in subjects with type 2 diabetes: reversal by exercise
training.
Diabetes. 2006 Mar;55(3):760-7.
PMID: 16505240
Musi
N, Goodyear LJ.
Insulin resistance and improvements in signal transduction.
Endocrine. 2006 Feb;29(1):73-80. Review.
PMID: 16622294
Musi
N.
AMP-activated protein kinase and type 2 diabetes.
Curr Med Chem. 2006;13(5):583-9. Review.
PMID: 16515522
Ahmad
F, Arad M, Musi N, He H, Wolf C, Branco D, Perez-Atayde AR, Stapleton D,
Bali D, Xing Y, Tian R, Goodyear LJ, Berul CI, Ingwall JS, Seidman CE,
Seidman JG.
Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy.
Circulation. 2005 Nov 15;112(20):3140-8. Epub 2005 Nov 7.
PMID: 16275868
Musi
N, Hirshman MF, Arad M, Xing Y, Fujii N, Pomerleau J, Ahmad F, Berul CI,
Seidman JG, Tian R, Goodyear LJ.
Functional role of AMP-activated protein kinase in the heart during
exercise.
FEBS Lett. 2005 Apr 11;579(10):2045-50.
PMID: 15811316
Fujii
N, Aschenbach WG, Musi N, Hirshman MF, Goodyear LJ.
Regulation of glucose transport by the AMP-activated protein kinase.
Proc Nutr Soc. 2004 May;63(2):205-10. Review.
PMID: 15294031
Musi
N, Goodyear LJ.
AMP-activated protein kinase and muscle glucose uptake.
Acta Physiol Scand. 2003 Aug;178(4):337-45. Review.
PMID: 12864738
Xing
Y, Musi N, Fujii N, Zou L, Luptak I, Hirshman MF, Goodyear LJ, Tian R.
Glucose metabolism and energy homeostasis in mouse hearts overexpressing
dominant negative alpha2 subunit of AMP-activated protein kinase.
J Biol Chem. 2003 Aug 1;278(31):28372-7. Epub 2003 May 23.
PMID: 12766162
Musi
N, Yu H, Goodyear LJ.
AMP-activated protein kinase regulation and action in skeletal muscle
during exercise.
Biochem Soc Trans. 2003 Feb;31(Pt 1):191-5. Review.
PMID: 12546683
Musi
N, Goodyear LJ.
Targeting the AMP-activated protein kinase for the treatment of type
2 diabetes.
Curr Drug Targets Immune Endocr Metabol Disord. 2002 Jul;2(2):119-27.
Review.
PMID: 12476786
Musi
N, Hirshman MF, Nygren J, Svanfeldt M, Bavenholm P, Rooyackers O, Zhou
G, Williamson JM, Ljunqvist O, Efendic S, Moller DE, Thorell A, Goodyear
LJ.
Metformin increases AMP-activated protein kinase activity in skeletal
muscle of subjects with type 2 diabetes.
Diabetes. 2002 Jul;51(7):2074-81.
PMID: 12086935
Tian
R, Musi N, D'Agostino J, Hirshman MF, Goodyear LJ.
Increased adenosine monophosphate-activated protein kinase activity
in rat hearts with pressure-overload hypertrophy.
Circulation. 2001 Oct 2;104(14):1664-9.
PMID: 11581146
Zhou
G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber
T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE.
Role of AMP-activated protein kinase in mechanism of metformin action.
J Clin Invest. 2001 Oct;108(8):1167-74.
PMID: 11602624
Musi
N, Hayashi T, Fujii N, Hirshman MF, Witters LA, Goodyear LJ.
AMP-activated protein kinase activity and glucose uptake in rat skeletal
muscle.
Am J Physiol Endocrinol Metab. 2001 May;280(5):E677-84.
PMID: 11287349
Musi
N, Fujii N, Hirshman MF, Ekberg I, Froberg S, Ljungqvist O, Thorell A,
Goodyear LJ.
AMP-activated protein kinase (AMPK) is activated in muscle of subjects
with type 2 diabetes during exercise.
Diabetes. 2001 May;50(5):921-7.
PMID: 11334434
Musi
N, Braverman LE, Norris CM Jr.
Severe thyrotoxicosis after parathyroid surgery for hyperparathyroidism.
Am J Med. 2000 Apr 15;108(6):519-20. No abstract available.
PMID: 10866589