Mamtani M, Rovin B, Brey R, Camargo JF, Kulkarni H, Herrera M, Correa P, Holliday S, Anaya JM, Ahuja SK.
CCL3L1 gene-containing segmental duplications and polymorphisms in CCR5 affect risk of systemic lupus erythematosus.
Ann Rheum Dis. 2007 Nov 1; [Epub ahead of print]
PMID: 17971457

Quinones MP, Martinez HG, Jimenez F, Estrada CA, Dudley M, Willmon O, Kulkarni H, Reddick RL, Fernandes G, Kuziel WA, Ahuja SK, Ahuja SS.
CC chemokine receptor 5 influences late-stage atherosclerosis.
Atherosclerosis. 2007 Nov;195(1):e92-103. Epub 2007 Apr 26.
PMID: 17466311

Dolan MJ, Kulkarni H, Camargo JF, He W, Smith A, Anaya JM, Miura T, Hecht FM, Mamtani M, Pereyra F, Marconi V, Mangano A, Sen L, Bologna R, Clark RA, Anderson SA, Delmar J, O'Connell RJ, Lloyd A, Martin J, Ahuja SS, Agan BK, Walker BD, Deeks SG, Ahuja SK.
CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms.
Nat. Immunol.. 2007 Oct 21; [Epub ahead of print]
PMID: 17952079

Quinones MP, Kalkonde Y, Estrada CA, Jimenez F, Ramirez R, Mahimainathan L, Mummidi S, Choudhury GG, Martinez H, Adams L, Mack M, Reddick RL, Maffi S, Haralambous S, Probert L, Ahuja SK, Ahuja SS.
Role of astrocytes and chemokine systems in acute TNFalpha induced demyelinating syndrome: CCR2-dependent signals promote astrocyte activation and survival via NF-kappaB and Akt.
Mol Cell Neurosci. 2007 Sep 14; [Epub ahead of print]
PMID: 17949991

Ketas TJ, Kuhmann SE, Palmer A, Zurita J, He W, Ahuja SK, Klasse PJ, Moore JP.
Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands.
Virology. 2007 Aug 1;364(2):281-90. Epub 2007 Apr 10.
PMID: 17428518

Mummidi S, Adams LM, VanCompernolle SE, Kalkonde M, Camargo JF, Kulkarni H, Bellinger AS, Bonello G, Tagoh H, Ahuja SS, Unutmaz D, Ahuja SK.
Production of specific mRNA transcripts, usage of an alternate promoter, and octamer-binding transcription factors influence the surface expression levels of the HIV coreceptor CCR5 on primary T cells.
J Immunol. 2007 May 1;178(9):5668-81.
PMID: 17442950

Quinones MP, Estrada CA, Jimenez F, Martinez H, Willmon O, Kuziel WA, Ahuja SK, Ahuja SS.
CCL2-independent role of CCR2 in immune responses against Leishmania major.
Parasite Immunol. 2007 Apr;29(4):211-7.
PMID: 17371458

Kalkonde YV, Morgan WW, Sigala J, Maffi SK, Condello C, Kuziel W, Ahuja SS, Ahuja SK.
Chemokines in the MPTP model of Parkinson's disease: absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration.
Brain Res. 2007 Jan 12;1128(1):1-11. Epub 2006 Nov 28.
PMID: 17126305

Silverberg MJ, Wegner SA, Milazzo MJ, McKaig RG, Williams CF, Agan BK, Armstrong AW, Gange SJ, Hawkes C, O'Connell RJ, Ahuja SK, Dolan MJ; Tri-Service AIDS Clinical Consortium Natural History Study Group.
Effectiveness of highly-active antiretroviral therapy by race/ethnicity.
AIDS. 2006 Jul 13;20(11):1531-8.
PMID: 16847408

Quinones MP, Jimenez F, Martinez H, Estrada CA, Willmon O, Dudley M, Kuziel WA, Melby PC, Reddick RL, Ahuja SK, Ahuja SS.
CC chemokine receptor (CCR)-2 prevents arthritis development following infection by Mycobacterium avium.
J Mol Med. 2006 Jun;84(6):503-12. Epub 2006 Mar 7.
PMID: 16520943

Sundrud MS, Vancompernolle SE, Eger KA, Bruno TC, Subramaniam A, Mummidi S, Ahuja SK, Unutmaz D.
Transcription factor GATA-1 potently represses the expression of the HIV-1 coreceptor CCR5 in human T cells and dendritic cells.
Blood. 2005 Nov 15;106(10):3440-8. Epub 2005 Aug 9.
PMID: 16091457

Quinones MP, Estrada CA, Kalkonde Y, Ahuja SK, Kuziel WA, Mack M, Ahuja SS.
The complex role of the chemokine receptor CCR2 in collagen-induced arthritis: implications for therapeutic targeting of CCR2 in rheumatoid arthritis.
J Mol Med. 2005 Sep;83(9):672-81. Epub 2005 Apr 13. Review.
PMID: 15827759

Burns JC, Shimizu C, Gonzalez E, Kulkarni H, Patel S, Shike H, Sundel RS, Newburger JW, Ahuja SK.
Genetic variations in the receptor-ligand pair CCR5 and CCL3L1 are important determinants of susceptibility to Kawasaki disease.
J Infect Dis. 2005 Jul 15;192(2):344-9. Epub 2005 Jun 8.
PMID: 15962231

Gonzalez E, Kulkarni H, Bolivar H, Mangano A, Sanchez R, Catano G, Nibbs RJ, Freedman BI, Quinones MP, Bamshad MJ, Murthy KK, Rovin BH, Bradley W, Clark RA, Anderson SA, O'connell RJ, Agan BK, Ahuja SS, Bologna R, Sen L, Dolan MJ, Ahuja SK.
The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility.
Science. 2005 Mar 4;307(5714):1434-40. Epub 2005 Jan 6.
PMID: 15637236

Ahuja SK, Catano G.
Sharing is caring, except when it comes to HLA-class-I alleles in HIV-1 transmission.
Lancet. 2004 Jun 26;363(9427):2103-4. No abstract available.
PMID: 15220030

Quinones MP, Ahuja SK, Jimenez F, Schaefer J, Garavito E, Rao A, Chenaux G, Reddick RL, Kuziel WA, Ahuja SS.
Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis.
J Clin Invest. 2004 Mar;113(6):856-66.
PMID: 15067318

Rao AR, Quinones MP, Garavito E, Kalkonde Y, Jimenez F, Gibbons C, Perez J, Melby P, Kuziel W, Reddick RL, Ahuja SK, Ahuja SS.
CC chemokine receptor 2 expression in donor cells serves an essential role in graft-versus-host-disease.
J Immunol. 2003 Nov 1;171(9):4875-85.
PMID: 14568968

Gonzalez E, Rovin BH, Sen L, Cooke G, Dhanda R, Mummidi S, Kulkarni H, Bamshad MJ, Telles V, Anderson SA, Walter EA, Stephan KT, Deucher M, Mangano A, Bologna R, Ahuja SS, Dolan MJ, Ahuja SK.
HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels.
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13795-800. Epub 2002 Oct 8.
PMID: 12374865

Bamshad MJ, Mummidi S, Gonzalez E, Ahuja SS, Dunn DM, Watkins WS, Wooding S, Stone AC, Jorde LB, Weiss RB, Ahuja SK.
A strong signature of balancing selection in the 5' cis-regulatory region of CCR5.
Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10539-44. Epub 2002 Jul 29.
PMID: 12149450

Mummidi S, Catano G, Lam L, Hoefle A, Telles V, Begum K, Jimenez F, Ahuja SS, Ahuja SK.
Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts.
J Biol Chem. 2001 Aug 31;276(35):33196-212. Epub 2001 May 3.
PMID: 11337487

Mangano A, Gonzalez E, Dhanda R, Catano G, Bamshad M, Bock A, Duggirala R, Williams K, Mummidi S, Clark RA, Ahuja SS, Dolan MJ, Bologna R, Sen L, Ahuja SK.
Concordance between the CC chemokine receptor 5 genetic determinants that alter risks of transmission and disease progression in children exposed perinatally to human immunodeficiency virus.
J Infect Dis. 2001 Jun 1;183(11):1574-85. Epub 2001 May 2.
PMID: 11335892

Gonzalez E, Dhanda R, Bamshad M, Mummidi S, Geevarghese R, Catano G, Anderson SA, Walter EA, Stephan KT, Hammer MF, Mangano A, Sen L, Clark RA, Ahuja SS, Dolan MJ, Ahuja SK.
Global survey of genetic variation in CCR5, RANTES, and MIP-1alpha: impact on the epidemiology of the HIV-1 pandemic.
Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5199-204.
PMID: 11320252

Melby PC, Ogden GB, Flores HA, Zhao W, Geldmacher C, Biediger NM, Ahuja SK, Uranga J, Melendez M.
Identification of vaccine candidates for experimental visceral leishmaniasis by immunization with sequential fractions of a cDNA expression library.
Infect Immun. 2000 Oct;68(10):5595-602.
PMID: 10992459

Quinones M, Ahuja SK, Melby PC, Pate L, Reddick RL, Ahuja SS.
Preformed membrane-associated stores of interleukin (IL)-12 are a previously unrecognized source of bioactive IL-12 that is mobilized within minutes of contact with an intracellular parasite.
J Exp Med. 2000 Aug 21;192(4):507-16.
PMID: 10952720

Sato N, Ahuja SK, Quinones M, Kostecki V, Reddick RL, Melby PC, Kuziel WA, Ahuja SS.
CC chemokine receptor (CCR)2 is required for langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 cytokines, b cell outgrowth, and sustained neutrophilic inflammation.
J Exp Med. 2000 Jul 17;192(2):205-18.
PMID: 10899907

Mummidi S, Bamshad M, Ahuja SS, Gonzalez E, Feuillet PM, Begum K, Galvis MC, Kostecki V, Valente AJ, Murthy KK, Haro L, Dolan MJ, Allan JS, Ahuja SK.
Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered transcription factor binding to polymorphic nucleotides in the pathogenesis of HIV-1 and simian immunodeficiency virus.
J Biol Chem. 2000 Jun 23;275(25):18946-61.
PMID: 10747879

Sato N, Kuziel WA, Melby PC, Reddick RL, Kostecki V, Zhao W, Maeda N, Ahuja SK, Ahuja SS.
Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-, macrophage inflammatory protein-1 alpha-, or CCR2-deficient mice.
J Immunol. 1999 Nov 15;163(10):5519-25.
PMID: 10553079

Gonzalez E, Bamshad M, Sato N, Mummidi S, Dhanda R, Catano G, Cabrera S, McBride M, Cao XH, Merrill G, O'Connell P, Bowden DW, Freedman BI, Anderson SA, Walter EA, Evans JS, Stephan KT, Clark RA, Tyagi S, Ahuja SS, Dolan MJ, Ahuja SK.
Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes.
Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12004-9.
PMID: 10518566

Ahuja SS, Mummidi S, Malech HL, Ahuja SK.
Human dendritic cell (DC)-based anti-infective therapy: engineering DCs to secrete functional IFN-gamma and IL-12.
J Immunol. 1998 Jul 15;161(2):868-76.
PMID: 9670965

Mummidi S, Ahuja SS, Gonzalez E, Anderson SA, Santiago EN, Stephan KT, Craig FE, O'Connell P, Tryon V, Clark RA, Dolan MJ, Ahuja SK.
Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression.
Nat Med. 1998 Jul;4(7):786-93.
PMID: 9662369

Mummidi S, Ahuja SS, McDaniel BL, Ahuja SK.
The human CC chemokine receptor 5 (CCR5) gene. Multiple transcripts with 5'-end heterogeneity, dual promoter usage, and evidence for polymorphisms within the regulatory regions and noncoding exons.
J Biol Chem. 1997 Dec 5;272(49):30662-71.
PMID: 9388201

Alkhatib G, Ahuja SS, Light D, Mummidi S, Berger EA, Ahuja SK.
CC chemokine receptor 5-mediated signaling and HIV-1 Co-receptor activity share common structural determinants. Critical residues in the third extracellular loop support HIV-1 fusion.
J Biol Chem. 1997 Aug 8;272(32):19771-6.
PMID: 9242636

Ahuja SK, Murphy PM.
The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor.
J Biol Chem. 1996 Aug 23;271(34):20545-50.
PMID: 8702798

Combadiere C, Ahuja SK, Tiffany HL, Murphy PM.
Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES.
J Leukoc Biol. 1996 Jul;60(1):147-52.
PMID: 8699119

Ahuja SS, Brown MR, Fleisher TA, Ahuja SK, Malech HL.
Autocrine activation of hemopoietic progenitor-derived myelo-monocytic cells by IFN-gamma gene transfer.
J Immunol. 1996 Jun 1;156(11):4345-53.
PMID: 8666806

Combadiere C, Ahuja SK, Murphy PM.
Cloning and functional expression of a human eosinophil CC chemokine receptor.
J Biol Chem. 1996 May 3;271(18):11034. No abstract available.
PMID: 8631926

Ahuja SK, Lee JC, Murphy PM.
CXC chemokines bind to unique sets of selectivity determinants that can function independently and are broadly distributed on multiple domains of human interleukin-8 receptor B. Determinants of high affinity binding and receptor activation are distinct.
J Biol Chem. 1996 Jan 5;271(1):225-32.
PMID: 8550564

Combadiere C, Ahuja SK, Van Damme J, Tiffany HL, Gao JL, Murphy PM.
Monocyte chemoattractant protein-3 is a functional ligand for CC chemokine receptors 1 and 2B.
J Biol Chem. 1995 Dec 15;270(50):29671-5.
PMID: 8530354

Combadiere C, Ahuja SK, Murphy PM.
Cloning, chromosomal localization, and RNA expression of a human beta chemokine receptor-like gene.
DNA Cell Biol. 1995 Aug;14(8):673-80.
PMID: 7646814

Combadiere C, Ahuja SK, Murphy PM.
Cloning and functional expression of a human eosinophil CC chemokine receptor.
J Biol Chem. 1995 Jul 14;270(28):16491-4. Erratum in: J Biol Chem 1995 Dec 15;270(50):30235. J Biol Chem. 1996 May 3;271(18):11034.
PMID: 7622448

Ahuja SK, Shetty A, Tiffany HL, Murphy PM.
Comparison of the genomic organization and promoter function for human interleukin-8 receptors A and B.
J Biol Chem. 1994 Oct 21;269(42):26381-9.
PMID: 7929358

Ahuja SK, Gao JL, Murphy PM.
Chemokine receptors and molecular mimicry.
Immunol Today. 1994 Jun;15(6):281-7. Review.
PMID: 8068175

Murphy PM, Tiffany HL, McDermott D, Ahuja SK.
Sequence and organization of the human N-formyl peptide receptor-encoding gene.
Gene. 1993 Nov 15;133(2):285-90.
PMID: 8224916

Ahuja SK, Murphy PM.
Molecular piracy of mammalian interleukin-8 receptor type B by herpesvirus saimiri.
J Biol Chem. 1993 Oct 5;268(28):20691-4.
PMID: 8407886

Ahuja SK, Ahuja SS, Thelmo W, Seymour A, Phelps KR.
Necrotizing pancreatitis and multisystem organ failure associated with toxoplasmosis in a patient with AIDS.
Clin Infect Dis. 1993 Mar;16(3):432-4.
PMID: 8452954

Ahuja SK, Ozcelik T, Milatovitch A, Francke U, Murphy PM.
Molecular evolution of the human interleukin-8 receptor gene cluster.
Nat Genet. 1992 Sep;2(1):31-6.
PMID: 1303245

Ahuja SS, Ahuja SK, Phelps KR, Thelmo W, Hill AR.
Hemodynamic confirmation of septic shock in disseminated tuberculosis.
Crit Care Med. 1992 Jun;20(6):901-3. No abstract available.
PMID: 1597048

Russell JC, Ahuja SK, Manickavel V, Rajotte RV, Amy RM.
Insulin resistance and impaired glucose tolerance in the atherosclerosis-prone LA/N corpulent rat.
Arteriosclerosis. 1987 Nov-Dec;7(6):620-6.
PMID: 3318782

Ahuja SK, Manickavel V, Amy RM, Russell JC.
Age-related qualitative and quantitative changes in the endocrine pancreas of the LA/N-corpulent rat.
Diabetes Res. 1987 Nov;6(3):137-44.
PMID: 3325219