|
Telephone: (210) 567-3754 E-mail: robinson@uthscsa.edu Structure-function relationships within mitochondrial electron transport complexes, particularly: 1) the role of cardiolipin and the nuclearly encoded subunits, and 2) the molecular basis for oxidative damage. |
Stanicova
J, Sedlak E, Musatov A, Robinson NC.
Differential stability of dimeric and monomeric cytochrome c oxidase
exposed to elevated hydrostatic pressure.
Biochemistry. 2007 Jun 19;46(24):7146-52. Epub 2007 May 26.
PMID: 17530783
Lemma-Gray
P, Weintraub ST, Carroll CA, Musatov A, Robinson NC.
Tryptophan 334 oxidation in bovine cytochrome c oxidase subunit I involves
free radical migration.
FEBS Lett. 2007 Feb 6;581(3):437-42. Epub 2007 Jan 12.
PMID: 17239857
McDonald-Marsh
T, Carroll CA, Robinson NC, Musatov A.
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
analysis of cardiolipin extracted from detergent-solubilized mitochondrial
electron transfer complexes.
Anal Biochem. 2006 Dec 15;359(2):262-4. Epub 2006 Sep 22. No
abstract available.
PMID: 17049476
Sedlak
E, Panda M, Dale MP, Weintraub ST, Robinson NC.
Photolabeling of cardiolipin binding subunits within bovine heart cytochrome
c oxidase.
Biochemistry. 2006 Jan 24;45(3):746-54.
PMID: 16411750
Stanicova
J, Musatov A, Robinson NC.
Stability of bovine cytochrome C oxidase as studied after exposure
to high hydrostatic pressure.
Acta Medica (Hradec Kralove). 2004;47(4):335-8.
PMID: 15841923 [PubMed - indexed for MEDLINE]
Musatov
A, Hebert E, Carroll CA, Weintraub ST, Robinson NC.
Specific modification of two tryptophans within the nuclear-encoded
subunits of bovine cytochrome c oxidase by hydrogen peroxide.
Biochemistry. 2004 Feb 3;43(4):1003-9.
PMID: 14744145 [PubMed - indexed for MEDLINE]
Musatov
A, Carroll CA, Liu YC, Henderson GI, Weintraub ST, Robinson NC.
Identification of bovine heart cytochrome c oxidase subunits modified
by the lipid peroxidation product 4-hydroxy-2-nonenal.
Biochemistry. 2002 Jun 25;41(25):8212-20.
PMID: 12069614 [PubMed - indexed for MEDLINE]
Musatov
A, Robinson NC.
Cholate-induced dimerization of detergent- or phospholipid-solubilized
bovine cytochrome C oxidase.
Biochemistry. 2002 Apr 2;41(13):4371-6.
PMID: 11914083 [PubMed - indexed for MEDLINE]
Musatov
A, Ortega-Lopez J, Robinson NC.
Detergent-solubilized bovine cytochrome c oxidase: dimerization depends
on the amphiphilic environment.
Biochemistry. 2000 Oct 24;39(42):12996-3004.
PMID: 11041865 [PubMed - indexed for MEDLINE]
Sedlak
E, Robinson NC.
Phospholipase A(2) digestion of cardiolipin bound to bovine cytochrome
c oxidase alters both activity and quaternary structure.
Biochemistry. 1999 Nov 9;38(45):14966-72.
PMID: 10555978 [PubMed - indexed for MEDLINE]
Musatov
A, Ortega-Lopez J, Demeler B, Osborne JP, Gennis RB, Robinson NC.
Detergent-solubilized Escherichia coli cytochrome bo3 ubiquinol oxidase:
a monomeric, not a dimeric complex.
FEBS Lett. 1999 Aug 20;457(1):153-6.
PMID: 10486584 [PubMed - indexed for MEDLINE]
Gomez
B Jr, Robinson NC.
Phospholipase digestion of bound cardiolipin reversibly inactivates
bovine cytochrome bc1.
Biochemistry. 1999 Jul 13;38(28):9031-8.
PMID: 10413476 [PubMed - indexed for MEDLINE]
Chen
J, Robinson NC, Schenker S, Frosto TA, Henderson GI.
Formation of 4-hydroxynonenal adducts with cytochrome c oxidase in
rats following short-term ethanol intake.
Hepatology. 1999 Jun;29(6):1792-8.
PMID: 10347122 [PubMed - indexed for MEDLINE]
Gomez
B Jr, Robinson NC.
Quantitative determination of cardiolipin in mitochondrial electron
transferring complexes by silicic acid high-performance liquid chromatography.
Anal Biochem. 1999 Feb 1;267(1):212-6.
PMID: 9918673 [PubMed - indexed for MEDLINE]
Liu
YC, Sowdal LH, Robinson NC.
Separation and quantitation of cytochrome c oxidase subunits by Mono-Q
fast protein liquid chromatography and C18 reverse-phase high-performance
liquid chromatography.
Arch Biochem Biophys. 1995 Dec 1;324(1):135-42.
PMID: 7503548 [PubMed - indexed for MEDLINE]
Panda
M, Robinson NC.
Kinetics and mechanism for the binding of HCN to cytochrome c oxidase.
Biochemistry. 1995 Aug 8;34(31):10009-18.
PMID: 7632673 [PubMed - indexed for MEDLINE]
Ortega-Lopez
J, Robinson NC.
Cytochrome c oxidase: biphasic kinetics result from incomplete reduction
of cytochrome a by cytochrome c bound to the high-affinity site.
Biochemistry. 1995 Aug 8;34(31):10000-8.
PMID: 7632672 [PubMed - indexed for MEDLINE]
Musatov
A, Robinson NC.
Detergent-solubilized monomeric and dimeric cytochrome bc1 isolated
from bovine heart.
Biochemistry. 1994 Nov 8;33(44):13005-12.
PMID: 7947705 [PubMed - indexed for MEDLINE]
Musatov
A, Robinson NC.
Subunit analysis of bovine cytochrome bc1 by reverse-phase HPLC and
determination of the subunit molecular masses by electrospray ionization
mass spectrometry.
Biochemistry. 1994 Sep 6;33(35):10561-7.
PMID: 8075056 [PubMed - indexed for MEDLINE]
Robinson
NC.
Functional binding of cardiolipin to cytochrome c oxidase.
J Bioenerg Biomembr. 1993 Apr;25(2):153-63. Review.
PMID: 8389748 [PubMed - indexed for MEDLINE]
Robinson
NC, Zborowski J, Talbert LH.
Cardiolipin-depleted bovine heart cytochrome c oxidase: binding stoichiometry
and affinity for cardiolipin derivatives.
Biochemistry. 1990 Sep 25;29(38):8962-9.
PMID: 2176838 [PubMed - indexed for MEDLINE]
Robinson
NC, Dale MP, Talbert LH.
Subunit analysis of bovine cytochrome c oxidase by reverse phase high
performance liquid chromatography.
Arch Biochem Biophys. 1990 Sep;281(2):239-44.
PMID: 2168156 [PubMed - indexed for MEDLINE]
Robinson
NC.
Silicic acid HPLC of cardiolipin, mono- and dilysocardiolipin, and
several of their chemical derivatives.
J Lipid Res. 1990 Aug;31(8):1513-6.
PMID: 2280191 [PubMed - indexed for MEDLINE]
Mahapatro
SN, Robinson NC.
Effect of changing the detergent bound to bovine cytochrome c oxidase
upon its individual electron-transfer steps.
Biochemistry. 1990 Jan 23;29(3):764-70.
PMID: 2159789 [PubMed - indexed for MEDLINE]
Dale
MP, Robinson NC.
Synthesis of cardiolipin derivatives with protection of the free hydroxyl:
its application to the study of cardiolipin stimulation of cytochrome c
oxidase.
Biochemistry. 1988 Oct 18;27(21):8270-5.
PMID: 2852959 [PubMed - indexed for MEDLINE]
Hill
BC, Cook K, Robinson NC.
Subunit dissociation and protein unfolding in the bovine heart cytochrome
oxidase complex induced by guanidine hydrochloride.
Biochemistry. 1988 Jun 28;27(13):4741-7.
PMID: 2844238 [PubMed - indexed for MEDLINE]
Hill
BC, Robinson NC.
Cyanide binding to bovine heart cytochrome c oxidase depleted of subunit
III by treatment with lauryl maltoside.
J Biol Chem. 1986 Nov 25;261(33):15356-9.
PMID: 3023317 [PubMed - indexed for MEDLINE]
Robinson
NC, Talbert L.
Triton X-100 induced dissociation of beef heart cytochrome c oxidase
into monomers.
Biochemistry. 1986 May 6;25(9):2328-35.
PMID: 3013301 [PubMed - indexed for MEDLINE]
Hill
BC, Horowitz PM, Robinson NC.
Detection, characterization, and quenching of the intrinsic fluorescence
of bovine heart cytochrome c oxidase.
Biochemistry. 1986 Apr 22;25(8):2287-92.
PMID: 3011084 [PubMed - indexed for MEDLINE]
Robinson
NC, Neumann J, Wiginton D.
Influence of detergent polar and apolar structure upon the temperature
dependence of beef heart cytochrome c oxidase activity.
Biochemistry. 1985 Oct 22;24(22):6298-304.
PMID: 3002436 [PubMed - indexed for MEDLINE]
Robinson
NC, Wiginton D.
Diphosphatidylglycerol reactivation of lipid-depleted beef heart cytochrome
c oxidase: effect of subunit III removal.
J Inorg Biochem. 1985 Mar-Apr;23(3-4):171-6.
PMID: 2991454 [PubMed - indexed for MEDLINE]
Robinson
NC, Wiginton D, Talbert L.
Phenyl-Sepharose-mediated detergent-exchange chromatography: its application
to exchange of detergents bound to membrane proteins.
Biochemistry. 1984 Dec 4;23(25):6121-6.
PMID: 6098309 [PubMed - indexed for MEDLINE]
Nelson
DR, Robinson NC.
Membrane proteins: a summary of known structural information.
Methods Enzymol. 1983;97:571-618. Review. No abstract available.
PMID: 6318035 [PubMed - indexed for MEDLINE]
Robinson
NC.
Specificity and binding affinity of phospholipids to the high-affinity
cardiolipin sites of beef heart cytochrome c oxidase.
Biochemistry. 1982 Jan 5;21(1):184-8. No abstract available.
PMID: 6277366 [PubMed - indexed for MEDLINE]
Robinson
NC, Strey F, Talbert L.
Investigation of the essential boundary layer phospholipids of cytochrome
c oxidase using Triton X-100 delipidation.
Biochemistry. 1980 Aug 5;19(16):3656-61. No abstract available.
PMID: 6250574 [PubMed - indexed for MEDLINE]
Robinson
NC, Talbert L.
Isolation of bovine cytochrome c1 as a single non-denatured subunit
using gel filtration or high pressure liquid chromatography in deoxycholate.
Biochem Biophys Res Commun. 1980 Jul 16;95(1):90-6. No abstract
available.
PMID: 6251811 [PubMed - indexed for MEDLINE]
Robinson
NC, Capaldi RA.
Interaction of detergents with cytochrome c oxidase.
Biochemistry. 1977 Feb 8;16(3):375-81.
PMID: 189798 [PubMed - indexed for MEDLINE]
Downer
NW, Robinson NC.
Characterization of a seventh different subunit of beef heart cytochrome
c oxidase. Similarities between the beef heart enzyme and that from other
species.
Biochemistry. 1976 Jun 29;15(13):2930-6.
PMID: 181053 [PubMed - indexed for MEDLINE]
Briggs
M, Kamp PF, Robinson NC, Capaldi RA.
The subunit structure of the cytochrome c oxidase complex.
Biochemistry. 1975 Nov 18;14(23):5123-8.
PMID: 172117 [PubMed - indexed for MEDLINE]
Visser
L, Robinson NC, Tanford C.
The two-domain structure of cytochrome b5 in deoxycholate solution.
Biochemistry. 1975 Mar 25;14(6):1194-9.
PMID: 1168068 [PubMed - indexed for MEDLINE]
Robinson
NC, Tanford C.
The binding of deoxycholate, Triton X-100, sodium dodecyl sulfate,
and phosphatidylcholine vesicles to cytochrome b5.
Biochemistry. 1975 Jan 28;14(2):369-78.
PMID: 1120108 [PubMed - indexed for MEDLINE]
Robinson
NC, Neurath H, Walsh KA.
Preparation and characterization of guanidinated trypsinogen and -guanidinated
trypsin.
Biochemistry. 1973 Jan 30;12(3):414-20. No abstract available.
PMID: 4734231 [PubMed - indexed for MEDLINE]
Robinson
NC, Neurath H, Walsh KA.
The relation of the -amino group of trypsin to enzyme function and
zymogen activation.
Biochemistry. 1973 Jan 30;12(3):420-6. No abstract available.
PMID: 4683488 [PubMed - indexed for MEDLINE]
Morgan
PH, Robinson NC, Walsh KA, Neurath H.
Inactivation of bovine trypsinogen and chymotrypsinogen by diisopropylphosphorofluoridate.
Proc Natl Acad Sci U S A. 1972 Nov;69(11):3312-6. No abstract
available.
PMID: 4508324 [PubMed - indexed for MEDLINE]
Robinson
NC, Tye RW, Neurath H, Walsh KA.
Isolation of trypsins by affinity chromatography.
Biochemistry. 1971 Jul 6;10(14):2743-7. No abstract available.
PMID: 5558697 [PubMed - indexed for MEDLINE]
