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Telephone: (210) 567-3743 E-mail: jewoe@biochem.uthscsa.edu Structural biology, RNA structure and function, RNA-protein interactions, RNA-ligand interactions, NMR-spectroscopy. Lecture materials for BIOC 6035: Biochemistry
of multimolecular complexes lecture 1.
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Buck
J, Furtig B, Noeske J, Wohnert J, Schwalbe H.
Time-resolved NMR methods resolving ligand-induced RNA folding at atomic
resolution.
Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15699-704. Epub
2007 Sep 25.
PMID: 17895388
Martin
LJ, Hahnke MJ, Nitz M, Wohnert J, Silvaggi NR, Allen KN, Schwalbe H, Imperiali
B.
Double-lanthanide-binding tags: design, photophysical properties, and
NMR applications.
J Am Chem Soc. 2007 Jun 6;129(22):7106-13. Epub 2007 May 12.
PMID: 17497862
Schwalbe
H, Buck J, Furtig B, Noeske J, Wohnert J.
Structures of RNA switches: insight into molecular recognition and
tertiary structure.
Angew Chem Int Ed Engl. 2007;46(8):1212-9. Review.
PMID: 17226886
Noeske
J, Schwalbe H, Wohnert J.
Metal-ion binding and metal-ion induced folding of the adenine-sensing
riboswitch aptamer domain.
Nucleic Acids Res. 2007;35(15):5262-73. Epub 2007 Aug 7.
PMID: 17686787
Noeske
J, Buck J, Furtig B, Nasiri HR, Schwalbe H, Wohnert J.
Interplay of 'induced fit' and preorganization in the ligand induced
folding of the aptamer domain of the guanine binding riboswitch.
Nucleic Acids Res. 2007;35(2):572-83. Epub 2006 Dec 14.
PMID: 17175531
Jonker
HR, Ilin S, Grimm SK, Wohnert J, Schwalbe H.
L11 domain rearrangement upon binding to RNA and thiostrepton studied
by NMR spectroscopy.
Nucleic Acids Res. 2007;35(2):441-54. Epub 2006 Dec 14.
PMID: 17169991
Ab
E, Atkinson AR, Banci L, Bertini I, Ciofi-Baffoni S, Brunner K, Diercks
T, Dotsch V, Engelke F, Folkers GE, Griesinger C, Gronwald W, Gunther U,
Habeck M, de Jong RN, Kalbitzer HR, Kieffer B, Leeflang BR, Loss S, Luchinat
C, Marquardsen T, Moskau D, Neidig KP, Nilges M, Piccioli M, Pierattelli
R, Rieping W, Schippmann T, Schwalbe H, Trave G, Trenner J, Wohnert J,
Zweckstetter M, Kaptein R.
NMR in the SPINE Structural Proteomics project.
Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1150-61.
Epub 2006 Sep 19. Review.
PMID: 17001092
Noeske
J, Richter C, Stirnal E, Schwalbe H, Wohnert J.
Phosphate-group recognition by the aptamer domain of the thiamine pyrophosphate
sensing riboswitch.
Chembiochem. 2006 Sep;7(9):1451-6.
PMID: 16871614
Ilin
S, Hoskins A, Ohlenschlager O, Jonker HR, Schwalbe H, Wohnert J.
Domain reorientation and induced fit upon RNA binding: solution structure
and dynamics of ribosomal protein L11 from Thermotoga maritima.
Chembiochem. 2005 Sep;6(9):1611-8.
PMID: 16094695 [PubMed - indexed for MEDLINE]
Grimm
SK, Wohnert J.
NMR assignments of the cold-shock protein ribosome-binding factor A
(RbfA) from Thermotoga maritima.
J Biomol NMR. 2005 Jan;31(1):73-4. No abstract available.
PMID: 15692745 [PubMed - indexed for MEDLINE]
Noeske
J, Richter C, Grundl MA, Nasiri HR, Schwalbe H, Wohnert J.
An intermolecular base triple as the basis of ligand specificity and
affinity in the guanine- and adenine-sensing riboswitch RNAs.
Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1372-7. Epub 2005
Jan 21.
PMID: 15665103 [PubMed - indexed for MEDLINE]
Duchardt
E, Richter C, Ohlenschlager O, Gorlach M, Wohnert J, Schwalbe H.
Determination of the glycosidic bond angle chi in RNA from cross-correlated
relaxation of CH dipolar coupling and N chemical shift anisotropy.
J Am Chem Soc. 2004 Feb 25;126(7):1962-70.
PMID: 14971929 [PubMed - indexed for MEDLINE]
Ohlenschlager
O, Wohnert J, Bucci E, Seitz S, Hafner S, Ramachandran R, Zell R, Gorlach
M.
The structure of the stemloop D subdomain of coxsackievirus B3 cloverleaf
RNA and its interaction with the proteinase 3C.
Structure. 2004 Feb;12(2):237-48.
PMID: 14962384 [PubMed - indexed for MEDLINE]
Wohnert
J, Franz KJ, Nitz M, Imperiali B, Schwalbe H.
Protein alignment by a coexpressed lanthanide-binding tag for the measurement
of residual dipolar couplings.
J Am Chem Soc. 2003 Nov 5;125(44):13338-9. No abstract available.
PMID: 14583012 [PubMed - indexed for MEDLINE]
Furtig
B, Richter C, Wohnert J, Schwalbe H.
NMR spectroscopy of RNA.
Chembiochem. 2003 Oct 6;4(10):936-62. Review.
PMID: 14523911 [PubMed - indexed for MEDLINE]
Wohnert
J, Gorlach M, Schwalbe H.
Triple resonance experiments for the simultaneous correlation of H6/H5
and exchangeable protons of pyrimidine nucleotides in 13C,15N-labeled RNA
applicable to larger RNA molecules.
J Biomol NMR. 2003 May;26(1):79-83.
PMID: 12766404 [PubMed - indexed for MEDLINE]
Ilin
S, Hoskins A, Schwalbe H, Wohnert J.
NMR assignment of the full-length ribosomal protein L11 from Thermotoga
maritima.
J Biomol NMR. 2003 Feb;25(2):163-4. No abstract available.
PMID: 12652127 [PubMed - indexed for MEDLINE]
Schlott
B, Wohnert J, Icke C, Hartmann M, Ramachandran R, Guhrs KH, Glusa E, Flemming
J, Gorlach M, Grosse F, Ohlenschlager O.
Interaction of Kazal-type inhibitor domains with serine proteinases:
biochemical and structural studies.
J Mol Biol. 2002 Apr 26;318(2):533-46.
PMID: 12051857 [PubMed - indexed for MEDLINE]
Smith
CK, Wohnert J, Sauer RT, Schwalbe H.
Assignments of the 1H,13C, and 15N resonances of the substrate-binding
SSD domain from Lon protease.
J Biomol NMR. 2001 Dec;21(4):387-8. No abstract available.
PMID: 11824761 [PubMed - indexed for MEDLINE]
Biali
SE, Bohmer V, Brenn J, Frings M, Thondorf I, Vogt W, Wohnert J.
Conformation, Inversion Barrier, and Solvent-Induced Conformational
Shift in Exo- and Endo/Exo-Calix[4]arenes.
J Org Chem. 1997 Nov 28;62(24):8350-8360.
PMID: 11671972 [PubMed - as supplied by publisher]
Agbaria
K, Wohnert J, Biali SE.
Extraannular fluorinated calixarenes: regiospecificity of the deoxofluorination
reactions of bis(spirodienol) derivatives.
J Org Chem. 2001 Oct 19;66(21):7059-66.
PMID: 11597230 [PubMed]
Mueller
F, Sommer I, Baranov P, Matadeen R, Stoldt M, Wohnert J, Gorlach M, van
Heel M, Brimacombe R.
The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli
50 S ribosomal subunit based on a cryo-electron microscopic reconstruction
at 7.5 A resolution.
J Mol Biol. 2000 Apr 21;298(1):35-59.
PMID: 10756104 [PubMed - indexed for MEDLINE]
Stoldt
M, Wohnert J, Ohlenschlager O, Gorlach M, Brown LR.
The NMR structure of the 5S rRNA E-domain-protein L25 complex shows
preformed and induced recognition.
EMBO J. 1999 Nov 15;18(22):6508-21.
PMID: 10562563 [PubMed - indexed for MEDLINE]
Wohnert
J, Dingley AJ, Stoldt M, Gorlach M, Grzesiek S, Brown LR.
Direct identification of NH...N hydrogen bonds in non-canonical base
pairs of RNA by NMR spectroscopy.
Nucleic Acids Res. 1999 Aug 1;27(15):3104-10.
PMID: 10454606 [PubMed - indexed for MEDLINE]
Wohnert
J, Ramachandran R, Gorlach M, Brown LR.
Triple-resonance experiments for correlation of H5 and exchangeable
pyrimidine base hydrogens in (13)C,(15)N-labeled RNA.
J Magn Reson. 1999 Aug;139(2):430-3.
PMID: 10423381 [PubMed - indexed for MEDLINE]
Stoldt
M, Wohnert J, Gorlach M, Brown LR.
The NMR structure of Escherichia coli ribosomal protein L25 shows homology
to general stress proteins and glutaminyl-tRNA synthetases.
EMBO J. 1998 Nov 2;17(21):6377-84.
PMID: 9799245 [PubMed - indexed for MEDLINE]
Wöhnert
,. Brenn J, Stoldt M, Aleksiuk O, Grynszpan F, Thondorf I and
Biali SE.
Conformation and stereodynamics of Monodioxamethylene Calix[4]arene
derivatives.
J. Org. Chem. 1998, 63: 3866-3874.